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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Adherence to antiretroviral therapy and clinical outcomes among young adults reporting high-risk sexual behavior, including men who have sex with men, in coastal Kenya
AIDS and Behavior, Volume 17, No. 4, Year 2013
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Description
African men who have sex with men (MSM) face significant stigma and barriers to care. We investigated antiretroviral therapy (ART) adherence among high-risk adults, including MSM, participating in a clinic-based cohort. Survival analysis was used to compare attrition across patient groups. Differences in adherence, weight gain, and CD4 counts after ART initiation were assessed. Among 250 HIV-1-seropositive adults, including 108 MSM, 15 heterosexual men, and 127 women, patient group was not associated with attrition. Among 58 participants who were followed on ART, 40 % of MSM had less than 95 % adherence, versus 28.6 % of heterosexual men and 11.5 % of women. Although MSM gained less weight after ART initiation than women (adjusted difference -3.5 kg/year), CD4 counts did not differ. More data are needed on barriers to adherence and clinical outcomes among African MSM, to ensure that MSM can access care and derive treatment and prevention benefits from ART. © 2013 Springer Science+Business Media New York.
Authors & Co-Authors
Graham, Susan Marie
United States, Seattle
University of Washington
Kenya, Kilifi
Centre for Geographic Medicine Research
Mugo, Peter Mwangi
Kenya, Kilifi
Centre for Geographic Medicine Research
Gichuru, Evans N.
Kenya, Kilifi
Centre for Geographic Medicine Research
Thiong'O, Alexander N.
Kenya, Kilifi
Centre for Geographic Medicine Research
MacHaria, Michael
Kenya, Kilifi
Centre for Geographic Medicine Research
Okuku, Haile Selassie
Kenya, Kilifi
Centre for Geographic Medicine Research
van der Elst, Elise Maria
Kenya, Kilifi
Centre for Geographic Medicine Research
Price, Matt A.
United States, New York
International Aids Vaccine Initiative
Muraguri, Nicholas M.
Kenya, Nairobi
National Aids
Sanders, Eduard Joachim
Kenya, Kilifi
Centre for Geographic Medicine Research
United Kingdom, Oxford
Nuffield Department of Medicine
Statistics
Citations: 66
Authors: 10
Affiliations: 5
Identifiers
Doi:
10.1007/s10461-013-0445-9
ISSN:
10907165
Research Areas
Health System And Policy
Infectious Diseases
Sexual And Reproductive Health
Study Design
Cohort Study
Study Locations
Kenya
Participants Gender
Male
Female