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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Comparison of isometamidium chloride and homidium bromide as prophylactic drugs for trypanosomiasis in cattle at Nguruman, Kenya
Acta Tropica, Volume 59, No. 2, Year 1995
Notification
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Description
The duration of prophylaxis provided by isometamidium chloride and homidium bromide, each at a dose rate of 1 mg kg-1 bodyweight, was compared in a 12-month field trial involving groups of 30 zebu cattle in south-west Kenya. The trial took place between February 1990 and February 1991 and included several months of high trypanosome challenge. Cattle in the prophylaxis groups were retreated on a group basis when 10% of the group had become infected since the previous group treatment. On this basis the mean intervals between retreatment were 7.5 ± 1.9 and 4.6 ± 2.1 weeks for the isometamidium and homidium groups, respectively. Weight gains in the two groups were similar. In spite of the need for more frequent treatment in the homidium group as compared to the isometamidium group, total drug costs were lower in the former. There was evidence of Trypanosoma congolense resistant to homidium and some evidence of T. vivax resistant to isometamidium. © 1995.
Authors & Co-Authors
Stevenson, Peter G.W.
Kenya
Kenya Trypanosomiasis Research Institute Ketri
Sones, K. R.
Kenya, Nairobi
Stock Watch Ltd.
Gicheru, Michael Muita
Kenya
Kenya Trypanosomiasis Research Institute Ketri
Mwangi, E. K.
Kenya
Kenya Trypanosomiasis Research Institute Ketri
Statistics
Citations: 44
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1016/0001-706X(94)00080-K
ISSN:
0001706X
Study Locations
Kenya