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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Worms can worsen malaria: Towards a new means to roll back malaria?
Trends in Parasitology, Volume 21, No. 8, Year 2005
Notification
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Description
Recent studies in Africa and Asia indicate that different helminthic infections adversely affect the clinical outcome of malaria infections. This suggests that helminths can influence the acquisition of immunity against Plasmodium. Worms could constitute a confounding factor in the assessment of efficacy of malaria-control intervention, including vaccine prototypes in clinical trials. These observations have fundamental and practical consequences; if the deleterious effect of worms on malaria is confirmed, treatment of helminths would offer an affordable, strongly effective and novel means to roll back malaria. With this article, we hope to induce others to conduct similar studies in different regions. © 2005 Elsevier Ltd. All rights reserved.
Authors & Co-Authors
Druilhe, Pierre L.
France, Paris
Institut Pasteur, Paris
Tall, Adama
Senegal, Dakar
Institut Pasteur de Dakar
Sokhna, Cheikh Sadibou
Senegal, Dakar
Institut de Recherche Pour le Développement Dakar
Statistics
Citations: 221
Authors: 3
Affiliations: 3
Identifiers
Doi:
10.1016/j.pt.2005.06.011
ISSN:
14714922
Research Areas
Infectious Diseases
Study Design
Randomised Control Trial