Pilomatricoma. A clinical, histopathologic and histochemical study of 22 patients

We have studied the clinical, histopathologic and histochemical features of pilornatricoma in a series of 22 cases. In early lesions, basophilic cells constituted the main tumor cell population and underwent four ways of maturation. Calcification was observed in 16 cases and ossification in two lesions. Melanin pigment was found in seven specimens and hemosiderin in six. Glycogen granules were present in most tumor parenchyma and less frequently in the stroma. Mitotic figures were frequent but cellular atypia was not observed. Copyright © 1994, Wiley Blackwell. All rights reserved