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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
The genetic prehistory of southern Africa
Nature Communications, Volume 3, Article 1143, Year 2012
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Description
Southern and eastern African populations that speak non-Bantu languages with click consonants are known to harbour some of the most ancient genetic lineages in humans, but their relationships are poorly understood. Here, we report data from 23 populations analysed at over half a million single-nucleotide polymorphisms, using a genome-wide array designed for studying human history. The southern African Khoisan fall into two genetic groups, loosely corresponding to the northwestern and southeastern Kalahari, which we show separated within the last 30,000 years. We find that all individuals derive at least a few percent of their genomes from admixture with non-Khoisan populations that began ∼1,200 years ago. In addition, the East African Hadza and Sandawe derive a fraction of their ancestry from admixture with a population related to the Khoisan, supporting the hypothesis of an ancient link between southern and eastern Africa. © 2012 Macmillan Publishers Limited. All rights reserved.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC3493647/bin/ncomms2140-s1.pdf
Authors & Co-Authors
Pickrell, Joseph K.
Unknown Affiliation
Patterson, Nick J.
Unknown Affiliation
Barbieri, Chiara
Unknown Affiliation
Berthold, Falko
Unknown Affiliation
Gerlach, Linda
Unknown Affiliation
Güldemann, Tom
Unknown Affiliation
Kure, Blesswell
Unknown Affiliation
Mpoloka, Sununguko Wata
Unknown Affiliation
Nakagawa, Hirosi
Unknown Affiliation
Naumann, Christfried
Unknown Affiliation
Lipson, Mark H.
Unknown Affiliation
Loh, Po Ru
Unknown Affiliation
Lachance, Joseph
Unknown Affiliation
Mountain, Joanna L.
Unknown Affiliation
Bustamante, Carlos Daniel
Unknown Affiliation
Berger, Bonnie A.
Unknown Affiliation
Tishkoff, Sarah A.
Unknown Affiliation
Henn, Brenna Mariah
Unknown Affiliation
Stoneking, Mark
Unknown Affiliation
Reich, David E.
Unknown Affiliation
Pakendorf, Brigitte
Unknown Affiliation
Statistics
Citations: 284
Authors: 21
Affiliations: 14
Identifiers
Doi:
10.1038/ncomms2140
e-ISSN:
20411723
Research Areas
Genetics And Genomics
Study Design
Cross Sectional Study