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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
general
The bonobo genome compared with the chimpanzee and human genomes
Nature, Volume 486, No. 7404, Year 2012
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Description
Two African apes are the closest living relatives of humans: the chimpanzee (Pan troglodytes) and the bonobo (Pan paniscus). Although they are similar in many respects, bonobos and chimpanzees differ strikingly in key social and sexual behaviours, and for some of these traits they show more similarity with humans than with each other. Here we report the sequencing and assembly of the bonobo genome to study its evolutionary relationship with the chimpanzee and human genomes. We find that more than three per cent of the human genome is more closely related to either the bonobo or the chimpanzee genome than these are to each other. These regions allow various aspects of the ancestry of the two ape species to be reconstructed. In addition, many of the regions that overlap genes may eventually help us understand the genetic basis of phenotypes that humans share with one of the two apes to the exclusion of the other. © 2012 Macmillan Publishers Limited. All rights reserved.
Authors & Co-Authors
Prüfer, Kay
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
Munch, Kasper
Denmark, Aarhus
Aarhus Universitet
Hellmann, Ines
Austria, Vienna
Universität Wien
Akagi, Keiko
United States, Columbus
The Ohio State University Comprehensive Cancer Center
Miller, Jason Rafe
United States, Rockville
J. Craig Venter Institute
Walenz, Brian P.
United States, Rockville
J. Craig Venter Institute
Koren, Sergey
United States, College Park
University of Maryland, College Park
Sutton, Granger G.
United States, Rockville
J. Craig Venter Institute
Kodira, Chinnappa Dilip
Unknown Affiliation
Winer, Roger
Unknown Affiliation
Knight, James R.
Unknown Affiliation
Mullikin, James C.
United States, Bethesda
National Human Genome Research Institute Nhgri
Meader, Stephen J.
United Kingdom, Oxford
University of Oxford
Ponting, Chris Paul
United Kingdom, Oxford
University of Oxford
Lunter, Gerton
United Kingdom, Oxford
The Wellcome Centre for Human Genetics
Higashino, Saneyuki
Japan, Tokyo
Tokyo Institute of Technology
Hobolth, Asger
Denmark, Aarhus
Aarhus Universitet
Dutheil, Julien
Denmark, Aarhus
Aarhus Universitet
Karakoc, Emre
United States, Seattle
University of Washington
Alkan, Can
United States, Seattle
University of Washington
Turkey, Ankara
Bilkent Üniversitesi
Sajjadian, Saba
United States, Seattle
University of Washington
Catacchio, Claudia Rita
Italy, Bari
Università Degli Studi Di Bari Aldo Moro
Ventura, Mario
United States, Seattle
University of Washington
Italy, Bari
Università Degli Studi Di Bari Aldo Moro
Marques-Bonet, Tomas
United States, Seattle
University of Washington
Spain, Barcelona
Csic-upf - Instituto de Biologia Evolutiva Ibe
Eichler, Evan E.
United States, Seattle
University of Washington
André, Claudine
Unknown Affiliation
Atencia, Rebeca
United States, Washington, D.c.
The Jane Goodall Institute
Mugisha, Lawrence
Uganda
Chimpanzee Sanctuary and Wildlife Conservation Trust Cswct
Junhold, Jörg
Germany, Leipzig
Zoo Leipzig
Patterson, Nick J.
United States, Boston
Harvard Medical School
Siebauer, Michael
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
Good, Jeffrey M.
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
United States, Missoula
University of Montana
Fischer, Anne H.
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
Kenya, Nairobi
International Centre of Insect Physiology and Ecology Nairobi
Ptak, Susan E.
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
Lachmann, Michael
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
Symer, David E.
United States, Columbus
The Ohio State University Comprehensive Cancer Center
Mailund, Thomas
Denmark, Aarhus
Aarhus Universitet
Schierup, Mikkel Heide
Denmark, Aarhus
Aarhus Universitet
Andrés, Aida M.
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
Kelso, Janet F.
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
Pääbo, Svante
Germany, Leipzig
Max-planck-institut Für Evolutionäre Anthropologie
Statistics
Citations: 41
Authors: 41
Affiliations: 20
Identifiers
Doi:
10.1038/nature11128
ISSN:
00280836
e-ISSN:
14764687
Research Areas
Genetics And Genomics
Sexual And Reproductive Health