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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Cultural adaptation and validation of the "kidney Disease and Quality of Life - Short Form (KDQOL-SF™) version 1.3" questionnaire in Egypt
BMC Nephrology, Volume 13, No. 1, Article 170, Year 2012
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Description
Background: Health Related Quality of Life (HRQOL) instruments need disease and country specific validation. In Arab countries, there is no specific validated questionnaire for assessment of HRQOL in chronic kidney disease (CKD) patients. The aim of this study was to present an Arabic translation, adaptation, and the subsequent validation of the kidney disease quality of life-short form (KDQOL-SF™) version 1.3 questionnaire in a representative series of Egyptian CKD patients. Methods. KDQOL-SF™ version 1.3 was translated into Arabic by two independent translators, and then subsequently translated back into English. After translation disparities were reconciled, the final Arabic questionnaire was tested by interviewing 100 pre-dialysis CKD (stage 1-4) patients randomly selected from outpatients attending the Nephrology clinic at the Main Alexandria University Hospital. Test re-test reliability was performed, with a subsample of 50 consecutive CKD patients, by two interviews 7 days apart and internal consistency estimated by Cronbach's α. Discriminant, concept, and construct validity were assessed. Results: All items of SF-36 met the criterion for internal consistency and were reproducible. Of the 10 kidney disease targeted scales, only three had Cronbach's α <0.7: quality of social interaction (0.23), work status (0.28), and cognitive function (0.60). All disease specific scales were reproducible. Results from discriminant validity showed that the study questionnaire could discriminate between patients' subgroups. As for concept validity, the correlation between all domains of the questionnaire with overall health ratewas significant for all domains except for the work status, sexual function, emotional wellbeing, and role emotional. Furthermore, the correlation between the disease specific domains and the two composite summaries of SF-36 (physical and mental composite summaries) was significant for all domains except for sexual function with mental composite summary. Construct validity was indicated by the observation that the majority of the domains of the kidney disease targeted scale of KDQOL-SF™ 1.3 were significantly inter-correlated. Finally, principal component analysis of the kidney disease targeted scale indicated that this part of the questionnaire could be summarized into 10 factors that together explained 70.9% of the variance. Conclusion: The results suggest that this Arabic version of the KDQOL-SF™ 1.3 questionnaire is a valid and reliable tool for use in Egyptian patients with CKD. © 2012 Abd ElHafeez et al.; licensee BioMed Central Ltd.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC3583144/bin/1471-2369-13-170-S1.pdf
https://efashare.b-cdn.net/share/pmc/articles/PMC3583144/bin/1471-2369-13-170-S2.docx
Authors & Co-Authors
Abd Elhafeez, S.
Egypt, Alexandria
High Institute of Public Health
Sallam, S. A.
Egypt, Alexandria
High Institute of Public Health
Gad, Zahira Metwally
Egypt, Alexandria
High Institute of Public Health
Zoccali, Carmine
Italy, Rome
Consiglio Nazionale Delle Ricerche
Torino, Claudia
Italy, Rome
Consiglio Nazionale Delle Ricerche
Tripepi, Giovanni Luigi
Italy, Rome
Consiglio Nazionale Delle Ricerche
Elwakil, Hala S.
Egypt, Alexandria
Faculty of Medicine
Awad, Noha M.
Egypt, Alexandria
High Institute of Public Health
Statistics
Citations: 46
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.1186/1471-2369-13-170
e-ISSN:
14712369
Research Areas
Disability
Health System And Policy
Noncommunicable Diseases
Sexual And Reproductive Health
Study Locations
Egypt