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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Cutaneous leishmaniasis due to Leishmania major involving the bone marrow in an AIDS patient in Burkina Faso
Annales de Dermatologie et de Venereologie, Volume 135, No. 5, Year 2008
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Description
Background: Leishmaniasis covers three well-individualized clinical variants, each due to individual species found in different geographic areas. Herein we report the first case of cutaneous leishmaniasis due to Leishmania major involving bone marrow in an AIDS patient in Burkina Faso. Case report: A 38-year-old HIV-positive man presented with generalized, copper-coloured, painless, infiltrated, itching, papulonodular lesions present over the previous 10 months. Skin biopsy confirmed the diagnosis of diffuse cutaneous leishmaniasis. The bone-marrow smear showed numerous leishmania. The culture was positive and L. major was identified. The patient was being treated with antiretroviral medication and a pentavalent antimonial compound. The disease progression consisted of attacks and remissions separated by an average of three weeks. Discussion: L. major is the Leishmania species identified in Burkina Faso. It is responsible for typical cutaneous leishmaniasis but particular clinical forms have been described in immunodeficient patients, especially with diffuse cutaneous involvement. The spread of L. major infection to bone marrow could represent a public health problem in our country, where the HIV epidemic is still not under control, and particular vigilance is thus called for. © 2008 Elsevier Masson SAS. All rights reserved.
Authors & Co-Authors
Barro-Traoré, Fatou
Burkina Faso, Ouagadougou
Service de Dermatologie et de Vénéréologie de Ouagadougou
Preney, Laure
France
Réseau Dermatrop de France
Traoré, Adama Z.
Burkina Faso, Ouagadougou
Service de Dermatologie et de Vénéréologie de Ouagadougou
Darie, Hervé
France
Réseau Dermatrop de France
Tapsoba, P.
Burkina Faso, Ouagadougou
Service de Dermatologie et de Vénéréologie de Ouagadougou
Bassolé, Armand M.
Burkina Faso, Ouagadougou
Service de Dermatologie et de Vénéréologie de Ouagadougou
Sawadogo, S.
Burkina Faso, Ouagadougou
Service de Dermatologie et de Vénéréologie de Ouagadougou
Niamba, Pascal Antoine
Burkina Faso, Ouagadougou
Service de Dermatologie et de Vénéréologie de Ouagadougou
Grosshans, E.
France, Strasbourg
Les Hôpitaux Universitaires de Strasbourg
Géniaux, Marc
France
Réseau Dermatrop de France
Statistics
Citations: 14
Authors: 10
Affiliations: 3
Identifiers
Doi:
10.1016/j.annder.2007.10.005
ISSN:
01519638
Research Areas
Health System And Policy
Infectious Diseases
Study Locations
Burkina Faso