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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Clonidine administered as adjuvant for bupivacaine in ilioinguinal- iliohypogastric nerve block does not prolong postoperative analgesia
Paediatric Anaesthesia, Volume 15, No. 7, Year 2005
Notification
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Description
Background: Coadministration of clonidine with local anesthetics is associated with improvement of the quality of peripheral nerve block and significant prolongation of postoperative analgesia. Better analgesia has been reported with clonidine in ilioinguinal nerve block compared with caudal use. The object of this study was to determine whether adding of 1 μg·kg-1 clonidine to bupivacaine 0.25% in ilioinguinal-iliohypogastric nerve block prolongs postoperative analgesia in children. Methods: Ninety-eight children ASA I-II aged between 1 and 12 years, scheduled for elective outpatient herniorrhaphy or orchidopexy were randomly allocated to receive an ilioinguinal-iliohypogastric nerve block either with 0.3 ml·kg-1 bupivacaine 0.25% plus 1 μg·kg-1 clonidine or only bupivacaine. Postoperative analgesic needs, time to the first analgesic supplementation and sedation score were assessed in hospital for 6 h postoperatively and at home by telephone call. Results: Demographic data were similar in both groups. There was no statistical difference in the rate of rescue analgesia between the two groups during the first six postoperative hours (20.4% group clonidine vs 30.6% group no clonidine) (P = 0.17). A slight decrease in systolic blood pressure during surgery was reported in the clonidine group. There was no difference in the scores of sedation between the two groups. At home, 10 patients in the clonidine group and nine patients in the nonclonidine group received analgesic medication. There was no difference between the two groups regarding the number of patients receiving analgesic rescue during the first 24 h (log rank = 0.39). Parental satisfaction was high in both groups. Conclusions: Our study failed to demonstrate any advantage in addition of 1 μ·kg-1 clonidine to 0.25% bupivacaine for ilioinguinal-iliohypogastric nerve block compared with bupivacaine 0.25% alone. © 2005 Blackwell Publishing Ltd.
Authors & Co-Authors
Kaabachi, Olfa
Tunisia, Sousse
Chu Sahloul
Tunisia, Manouba
Université de Tunis el Manar, Institut Mohamed Kassab D'orthopédie
Zerelli, Zied
Tunisia, Sousse
Chu Sahloul
Methamem, Mehdi
Tunisia, Sousse
Chu Sahloul
Ben Abdelaziz, Ahmed
Tunisia, Sousse
Hopital Farhat Hached Sousse
Moncer, Khaled
Tunisia, Sousse
Chu Sahloul
Toumi, Mohsen
Tunisia, Sousse
Chu Sahloul
Statistics
Citations: 46
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1111/j.1460-9592.2005.01497.x
ISSN:
11555645
Research Areas
Health System And Policy
Maternal And Child Health
Noncommunicable Diseases