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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
High prevalence of asymptomatic Plasmodium falciparum infection in Gabonese adults
American Journal of Tropical Medicine and Hygiene, Volume 77, No. 5, Year 2007
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Description
Plasmodium falciparum, the most common malarial parasite in sub-Saharan Africa, accounts for a high number of deaths in children less than five years of age. In malaria-endemic countries with stable transmission, semi-immunity is usually acquired after childhood. For adults, severe malaria is rare. Infected adults have either uncomplicated malaria or asymptomatic parasitemia. During a period of one year, we screened 497 afebrile males to investigate the prevalence of asymptomatic P. falciparum parasitemia in villages near Lambaré né, Gabon by use of three different methods. A total of 52% of the individuals had parasites detected by a subtelomeric variable open reading frame polymerase chain reaction (stevor-PCR), 27% of the rapid diagnostic test results were positive, and 12% of the thick blood smears with low parasitemias had P. falciparum. Most positive cases were only detected by the stevor-PCR. Asymptomatic P. falciparum parasitemia in adults living in a malaria-endemic country is frequent. Copyright © 2007 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Dal-Bianco, Matthias P.
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Germany, Tubingen
Eberhard Karls Universität Tübingen
Köster, Kai B.
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Kombila, Ulrich Davy
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Kun, Juergen F.J.
Germany, Tubingen
Eberhard Karls Universität Tübingen
Grobusch, Martín Peter
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
South Africa, Johannesburg
School of Pathology
Mombo-Ngoma, Ghyslain
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Matsiégui, Pierre Blaise
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Germany, Tubingen
Eberhard Karls Universität Tübingen
Supan, Christian
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Ospina Salazar, Carmen Lucelly
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Missinou, Michel Anoumou
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Germany, Tubingen
Eberhard Karls Universität Tübingen
Issifou, Saadou
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Germany, Tubingen
Eberhard Karls Universität Tübingen
Lell, Bertrand
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Germany, Tubingen
Eberhard Karls Universität Tübingen
Kremsner, Peter G.
Gabon, Lambarene
Unité de Recherche Médicale, Albert Schweitzer Hospital
Germany, Tubingen
Eberhard Karls Universität Tübingen
Statistics
Citations: 111
Authors: 13
Affiliations: 3
Identifiers
Doi:
10.4269/ajtmh.2007.77.939
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Study Locations
Gabon