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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Sub-Saharan Rubiaceae: A Review of Their Traditional Uses, Phytochemistry and Biological Activities
Pakistan Journal of Biological Sciences, Volume 14, No. 3, Year 2011
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Description
Rubiaceae family is a large family of 630 genera and about 13000 species found worldwide, especially in tropical and warm regions. These plants are not only ornamental but they are also used in African folk medicine to treat several diseases. Based on online published data and library bibliographic research, we herein reported accumulated information related to their traditional usages in sub-Saharan traditional medicine, their chemical composition and the screened pharmacological activities. Indeed, more than 60 species are used for more than 70 medicinal indications including malaria, hepatitis, eczema, oedema, cough, hypertension, diabetes and sexual weakness. Through biological screening following leads supplied with traditional healers, many of these plants exhibited antimalarial, antimicrobial, antihypertension, anti diabetic, antioxidant and anti-inflammatory activities. Bioactive compounds including indole alkaloids, terpenoids and anthrax quinones have been isolated from these bioguided fractionation studies. It is evidence that great attention has been paid to species such as Nauclea latifolia, Morinda lucida, Mitragyna inermis and Cross opteryx febrifuga; however, several compounds should be waiting to be discovered since none of these plants has been systematically investigated for its biochemical composition. According the current global health context with the recrudescence of BTV, much effort should be oriented towards this virus when screening Rubiaceae. © 2011 Asian Network for Scientific Information.
Authors & Co-Authors
Karou, Simplice Damintoti
Togo, Lome
Centre Hospitalier Universitaire Tokoin
Burkina Faso, Ouagadougou
Centre de Recherche Biomoléculaire Pietro Annigoni Cerba
Tchacondo, Tchadjobo
Togo, Lome
Centre Hospitalier Universitaire Tokoin
Ilboudo, Dénise Patoinewende
Burkina Faso, Ouagadougou
Centre de Recherche Biomoléculaire Pietro Annigoni Cerba
Simpore, J.
Burkina Faso, Ouagadougou
Centre de Recherche Biomoléculaire Pietro Annigoni Cerba
Statistics
Citations: 120
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.3923/pjbs.2011.149.169
e-ISSN:
18125735
Research Areas
Health System And Policy
Infectious Diseases
Noncommunicable Diseases
Sexual And Reproductive Health