Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Plasmodium vivax and Plasmodium falciparum infections in the Republic of Djibouti: Evaluation of their prevalence and potential determinants
Malaria Journal, Volume 11, Article 395, Year 2012
Notification
URL copied to clipboard!
Description
Background: Formerly known as a hypoendemic malaria country, the Republic of Djibouti declared the goal of pre-eliminating malaria in 2006. The aim of the present study was to evaluate the prevalence of Plasmodium falciparum, Plasmodium vivax and mixed infections in the Djiboutian population by using serological tools and to identify potential determinants of the disease and hotspots of malaria transmission within the country. Methods. The prevalence of P. falciparum and P. vivax within the districts of the capital city and the rest of the Republic of Djibouti were assessed using 13 and 2 serological markers, respectively. The relationship between the immune humeral response to P. falciparum and P. vivax and variables such as age, gender, wealth status, urbanism, educational level, distance to rivers/lakes, living area, having fever in the last month, and staying in a malaria-endemic country more than one year was estimated and analysed by questionnaires administered to 1910 Djiboutians. Multivariate ordinal logistic regression models of the immune humeral response were obtained for P. falciparum and P. vivax. Results: The P. falciparum and P. vivax seroprevalence rates were 31.5%, CI95% [29.4-33.7] and 17.5%, CI95% [15.8-19.3], respectively. Protective effects against P. falciparum and P. vivax were female gender, educational level, and never having visited a malaria-endemic area for more than one year. For P. falciparum only, a protective effect was observed for not having a fever in the last month, living more than 1.5 km away from lakes and rivers, and younger ages. Conclusions: This is the first study that assessed the seroprevalence of P. vivax in the Republic of Djibouti. It is necessary to improve knowledge of this pathogen in order to create an effective elimination programme. As supported by recent observations on the subject, the Republic of Djibouti has probably demonstrated a real decrease in the transmission of P. falciparum in the past seven years, which should encourage authorities to improve efforts toward elimination. © 2012 Khaireh et al.; licensee BioMed Central Ltd.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S1.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S2.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S3.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S4.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S5.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S6.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S7.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S8.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S9.doc
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S10.tiff
https://efashare.b-cdn.net/share/pmc/articles/PMC3544601/bin/1475-2875-11-395-S11.tiff
Authors & Co-Authors
Khaireh, Bouh Abdi
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
France, Marseille
Unité de Recherche Sur Les Maladies Infectieuses et Tropicales Emergentes
Djibouti, Djibouti
Service de Santé Des Armées
Djibouti, Djibouti
Hôpital Général Peltier
Djibouti, Djibouti
Centre D'etudes et de Recherche de Djibouti
Briolant, Sébastien
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
France, Marseille
Unité de Recherche Sur Les Maladies Infectieuses et Tropicales Emergentes
Pascual, Aurélie M.
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
France, Marseille
Unité de Recherche Sur Les Maladies Infectieuses et Tropicales Emergentes
Mokrane, Madjid
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
France, Marseille
Unité de Recherche Sur Les Maladies Infectieuses et Tropicales Emergentes
MacHault, Vanessa
France, Toulouse
Université Toulouse Iii - Paul Sabatier
France, Paris
Cnes Centre National D'etudes Spatiales
Travaillé, Christelle
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
Khaireh, Mohamed Abdi
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
France, Marseille
Unité de Recherche Sur Les Maladies Infectieuses et Tropicales Emergentes
Farah, Ismaïl Hassan
Djibouti, Djibouti
Service de Santé Des Armées
Ali, Habib Moussa
Djibouti, Djibouti
Service de Santé Des Armées
Abdi, Abdoul Ilah Ahmed
Djibouti, Djibouti
Service de Santé Des Armées
Ayeh, Souleiman Nour
Djibouti, Djibouti
Hôpital Général Peltier
Darar, Houssein Youssouf
Djibouti, Djibouti
Hôpital Général Peltier
Djibouti, Djibouti
Ministère de la Santé
Ollivier, Lénaïck
France, Paris
Bureau Expertise Des Risques Sanitaires
Kileh-Wais, Mohamed Killeh
Djibouti, Djibouti
Université de Djibouti
Bogreau, Hervé
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
France, Marseille
Unité de Recherche Sur Les Maladies Infectieuses et Tropicales Emergentes
Rogier, Christophe
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
France, Marseille
Unité de Recherche Sur Les Maladies Infectieuses et Tropicales Emergentes
Madagascar, Antananarivo
Institut Pasteur de Madagascar
Pradines, Bruno
France, Bretigny-sur-orge
Institut de Recherche Biomédicale Des Armées
France, Marseille
Unité de Recherche Sur Les Maladies Infectieuses et Tropicales Emergentes
Statistics
Citations: 17
Authors: 17
Affiliations: 11
Identifiers
Doi:
10.1186/1475-2875-11-395
e-ISSN:
14752875
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study
Study Locations
Djibouti
Participants Gender
Female