Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

immunology and microbiology

Co-transmission of Related Malaria Parasite Lineages Shapes Within-Host Parasite Diversity

Cell Host and Microbe, Volume 27, No. 1, Year 2020

In high-transmission regions, malaria infections are expected to comprise unrelated parasite lineages due to parasite inoculations from different mosquitoes. Using single-cell genome sequencing, Nkhoma et al. find parasite lineages within infections to be closely related, indicating that co-transmission predominantly shapes within-host malaria parasite diversity.
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Citations: 55
Authors: 13
Affiliations: 5
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Research Areas
Infectious Diseases