Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Biochemical observations in rats fed with cycads, Nigerian-like and western-like folic acid supplemented diets
African Journal of Biotechnology, Volume 10, No. 41, Year 2011
Notification
URL copied to clipboard!
Description
Alterations in antioxidant enzymes and lipid peroxidation was studied in 90 Wistar albino rats exposed to cycads and fed with Nigerian-like and western-like diets supplemented with folic acid. The animals were divided into three diet classes of 30 animals each. One group was fed with a wholly compounded Nigerian-like diet (NLD) which was low in protein and high in carbohydrate and fiber. Another group was fed with a western like diet (WLD) which was high in protein and fat, while the third group of animals was fed with a normal diet which served as the control class. The animals of each class were further divided into three subgroups of ten rats each. In each subclass, one group received the diet alone; another group received the diet and cycads, while the third group received the diet and folic acid. Low levels of catalase, feed intake and faecal output was observed with experimental animals fed NLD as compared to WLD and normal diet (ND) fed animals. High levels of antioxidant enzymes: super oxide dismutase, catalase and glutathione reductase as well as low levels of lipid peroxidation was observed with the addition of folic acid to the diets of experimental rats. These results suggest the role of folic acid in diet and colon carcinogenesis. © 2011 Academic Journals.
Authors & Co-Authors
Inegbedion, Augusta O.
Nigeria, Ekpoma
Ambrose Alli University
Eriyamremu, George Edaghogho
Nigeria, Benin
University of Benin
Prophet, Prohp The
Nigeria, Amassoma
Niger Delta University
Inegbenebor, Ute
Nigeria, Ekpoma
Ambrose Alli University
Okoro, Israel Oghenevwodokohwo
Nigeria, Abraka
Delta State University Nigeria
Osagie, Roland O.
Nigeria, Ekpoma
Ambrose Alli University
Statistics
Citations: 6
Authors: 6
Affiliations: 4
Identifiers
Doi:
10.5897/ajb11.1026
ISSN:
16845315
Research Areas
Cancer