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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
chemistry
Two new antimicrobial dimeric compounds: Febrifuquinone, a vismione-anthraquinone coupled pigment and adamabianthrone, from two Psorospermum species
Chemical and Pharmaceutical Bulletin, Volume 57, No. 10, Year 2009
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Description
Febrifuquinone (1), a new vismione-anthraquinone coupled pigment and a new bianthrone named adamabianthrone (2), were isolated respectively, from the roots of Psorospermum febrifugum and from the bark of Psorospermum adamauense along with eight known compounds including: two bianthrones [(bianthrone A1 (3) and bianthrone A2b], one vismione [(vismione D (4)], one anthrone (3-geranyloxyemodin anthrone) and four anthraquinones [(1,8-dihydroxy-3-isoprenyloxy-6-methylanthraquinone, emodin (5), 3-geranyloxy-1,8-dihydroxy-6-methylanthraquinone and 2-geranyl-1,8-dihydroxy-6- methylanthraquinone]. Their structures were determined using modern spectroscopic methods including one and two dimensional-NMR techniques as well as MS. Compounds 1 and 2 showed significant antimicrobial activities against a wide range of bacteria and fungi. © 2009 Pharmaceutical Society of Japan.
Authors & Co-Authors
Tsaffack, Maurice
Cameroon, Yaounde
Université de Yaoundé I
Nguemeving, Jean Robert
Cameroon, Yaounde
Université de Yaoundé I
Kuete, Victor
Cameroon, Dschang
Dschang University
Ndejouong Tchize, Basile Le Sage
Germany, Jena
Leibniz-institut Für Naturstoff-forschung Und Infektionsbiologie E. V. – Hans-knöll-institut
Mkounga, Pierre
Cameroon, Yaounde
Université de Yaoundé I
Penlap-Beng, Véronique Penlap
Cameroon, Yaounde
Université de Yaoundé I
Hultin, Philip Gregory
Canada, Winnipeg
University of Manitoba
Tsamo, Etienne
Cameroon, Yaounde
Université de Yaoundé I
Nkengfack, Augustin Ephrem
Cameroon, Yaounde
Université de Yaoundé I
Statistics
Citations: 30
Authors: 9
Affiliations: 4
Identifiers
Doi:
10.1248/cpb.57.1113
ISSN:
00092363
e-ISSN:
13475223