Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
High serum organochlorine pesticide concentrations in diabetics of a cotton producing area of the Benin Republic (West Africa)
Environment International, Volume 69, Year 2014
Notification
URL copied to clipboard!
Description
The Borgou region of northern Benin is a major cotton producing area and consistently uses higher amounts of pesticides than other areas of the country. Organochlorine pesticides (OCPs), poorly handled, have been widely used and are still illegally present. We therefore hypothesized that serum OCP levels would be high in Borgou. As part of a case-control study on diabetes status and pesticide exposure, we measured the distribution of serum concentrations of 14 OCPs by gas chromatography with mass spectrometry. A sample of 118 diabetic subjects was selected using a four-stage cluster sampling with 54.2% of men and 45.8% of women; 43% lived in urban areas, 14.4% were obese and 39.8% had high economic status. The four detected OCPs were p,. p'-DDT, p,. p'-DDE, β-HCH and trans-nonachlor with respective geometric means (geometric standard deviation) of 497.1 (4.5), 20.6 (7.9), 2.9 (3.4), and 2.0 (2.3) ng/g of total serum lipids. OCP levels were significantly higher in obese, wealthier and more educated subjects and in those living in urban areas as compared to the other groups, particularly for p,. p'-DDE, p,. p'-DDT and β-HCH. Levels of DDT and DDE were higher than reported in other countries where DDT is no longer permitted. The low DDT/DDE ratio of 0.05 suggests past human exposure through food contamination. There is thus a need to reinforce governmental regulations for a more responsible use of pesticides in the country, in order to reduce health risks associated with persistent organic pollutants. © 2014.
Authors & Co-Authors
Azandjèmè, Colette Sylvie
Canada, Montreal
University of Montreal
Benin, Cotonou
University of Abomey-calavi
Delisle, Hélène F.
Canada, Montreal
University of Montreal
Fayomi, Benjamin Eboum
Benin, Cotonou
University of Abomey-calavi
Ayotte, Pierre
Canada, Quebec
Institut National de Sante Publique du Québec
Canada, Quebec
Centre de Recherche du Chu de Québec-université Laval
Djrolo, François
Benin, Cotonou
University of Abomey-calavi
Benin
National University Hospital Cnhu-hkm
Houinato, Dismand Stephan
Benin, Cotonou
University of Abomey-calavi
Benin
Benin Republic National Program of Non Communicable Diseases
Bouchard, Michele
Canada, Montreal
University of Montreal
Statistics
Citations: 28
Authors: 7
Affiliations: 6
Identifiers
Doi:
10.1016/j.envint.2014.04.002
Research Areas
Environmental
Food Security
Noncommunicable Diseases
Study Design
Case-Control Study
Study Locations
Multi-countries
Benin
Participants Gender
Male
Female