Antibacterial activity of two flavonoids isolated from Schotia latifolia

Scholia latifolia Jacq is one of the plants commonly used in folkloric medicine for the treatment of tickborne diseases of livestock in the Eastern Cape Province of South Africa. Two flavonoids, epicatechin and catechin, were isolated from the bark of this plant through bioactivity-guided fractionation of its extracts. The compounds were active against Gram-positive and Gram-negative bacteria exhibiting minimum inhibitory concentrations ranging from 62.5 to 250 μg/ml.