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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
chemistry
Solubility of salbutamol and salbutamol sulphate in ethanol + water mixtures at 25 °c
Journal of Molecular Liquids, Volume 173, Year 2012
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Description
Experimental solubilities of salbutamol and salbutamol sulphate in ethanol + water mixtures at 25 °C are reported. The solubility of salbutamol was found to increase with the addition of ethanol, and reached a maximum value at an ethanol volume fraction of 0.8. The solubility of salbutamol sulphate decreased with increasing ethanol concentration, and reached a minimum value in ethanol. The Jouyban-Acree model correlated the measured salbutamol and salbutamol sulphate solubility data to within mean relative deviations (MRD) of 3.4% and 13.4%, respectively. Solubilities were predicted using previously trained models developed for crystalline non-electrolyte and electrolyte solutes. The trained models for non-electrolytes and electrolytes produced the prediction MRDs of 22.4% and 19.8%, respectively. Crown Copyright © 2012 Published by Elsevier B.V. All rights reserved.
Authors & Co-Authors
Ali, Hany Saleh M.
Egypt, Asyut
Faculty of Pharmacy
York, Peter
United Kingdom, Bradford
University of Bradford
Blagden, Nicholas
United Kingdom, Bradford
University of Bradford
Khoubnasabjafari, Maryam
Iran, Tabriz
Tuberculosis and Lung Diseases Research Center
Acree, William E.
United States, Denton
University of North Texas
Jouyban, Abolghasem
Iran, Tabriz
Drug Applied Research Center, Tabriz University of Medical Sciences
Statistics
Citations: 17
Authors: 6
Affiliations: 5
Identifiers
Doi:
10.1016/j.molliq.2012.05.021
ISSN:
01677322
Research Areas
Environmental