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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Quantification and comparison of psychiatric distress in African patients with albinism and vitiligo: A 5-year prospective study
Journal of the European Academy of Dermatology and Venereology, Volume 28, No. 7, Year 2014
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Description
Background Vitiligo and Albinism are two disorders of pigmentation that make the affected African highly visible and strikingly different from their peers. Both pose considerable management challenges, attract significant stigma and profound impairment of quality of life. Objective and Methods To determine and compare psychiatric distress in vitiligo and albinism using the Hospital Anxiety and Depression Scale (HADS). Participants were 87 albinos and 102 vitiligo adult patients seen at an urban tertiary hospital in Nigeria between 2004 and 2009. Results Prevalence of psycho morbidity was 59% (60/102) in vitiligo compared with 26% (23/87) in the albinos. The mean anxiety score was estimated to be 2.55 points lower for albino patients (95% CI: 1.47 to 3.64), and the mean depression score 2.76 points lower (95% CI: 1.84 to 3.68), after adjustment for age, sex and marital status. However, significant differences were not observed when comparing the vitiligo patients with the subset of albino patients with skin cancer. Older patients had significantly higher anxiety and depression scores. Females had significantly higher anxiety scores (but not depression scores) compared to males. Genital involvement in vitiligo was significantly associated with anxiety but not depression. Conclusions We found that the African with vitiligo suffers significantly higher psychiatric distress than the African albino on average. Clinical evaluation of these patients would be incomplete without assessment of their psycho morbidity. There is need for increased focus on cancer prevention strategies in the African albino. © 2013 European Academy of Dermatology and Venereology.
Authors & Co-Authors
Ajose, Frances O.A.
Nigeria, Lagos
Lagos State University
Parker, R. A.
United Kingdom, Cambridge
Cambridge Institute of Public Health
Merrall, E. L.C.
United Kingdom, Cambridge
Cambridge Institute of Public Health
Adewuya, Abiodun Olugbenga
Nigeria, Lagos
Lagos State University
Zachariah, Mathew P.
Nigeria, Lagos
Lagos State University
Statistics
Citations: 26
Authors: 5
Affiliations: 2
Identifiers
Doi:
10.1111/jdv.12216
ISSN:
09269959
e-ISSN:
14683083
Research Areas
Cancer
Disability
Health System And Policy
Mental Health
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Nigeria
Participants Gender
Female