Electrochemical behaviors and determination of carbidopa on carbon nanotubes ionic liquid paste electrode

Electrochemical behaviors of carbidopa (CD) at the surface of the carbon nanotubes paste electrode modified with an ionic liquid of 1-methyl-3- butylimidazolium bromide (MBIDZBr) were studied. The oxidation peak potential of the CD at a surface of the ionic liquid carbon nanotubes paste electrode (IL/CNTPE) appeared at 555 mV that was about 68 mV lower than the oxidation peak potential at the surface of the traditional carbon paste electrode (CPE) under similar condition. On other hand, the oxidation peak current was increased for about three times at the surface of IL/CNTPE compared to CPE. The linear response range and detection limit were found to be 0.1-420 μmol L -1 and 0.06 μmol L -1, respectively. Another physiological species did not interfere for determination of CD at a surface of propose sensor in the optimum condition. The proposed sensor was successfully applied for the determination of CD in real samples such as human urine and serum. © 2012 Elsevier B.V. All rights reserved.