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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Evaluation of antioxidant activity, total phenolic and flavonoid contents of Entada africana guill. et Perr. (Mimosaceae) organ extracts
Research Journal of Medical Sciences, Volume 4, No. 2, Year 2010
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Description
Entada africana is an endangered West African medicinal plant because of a large scale use of its roots. To evaluate and compare the medicinal potential of all plant parts for a sustainable use the radical scavenging activity (DPPH method) and the phenolic compound contents (Folin-Ciocalteu method) of aerial parts and roots were investigated. Aqueous extracts of leaves, stem barks and roots were used for this investigation. Methanol extract was also used for the roots. The fourth extracts showed high radical scavenging activity (ranging from 1.27-3.36 μg LL-1) similar to those of quercetin, rutoside and ascorbic acid (0.8, 5.20 and 5.32 μg mL-1, respectively). Fractions obtained from the four extracts with chloroform, ethyl acetate, methanol and water also showed high activity with EC, ranging from 3.39-16.72 pg mL-1 except chloroform fractions (EC50>36 μg mL-1). The total phenolic and flavonoid contents of the four extracts and their twelve fractions were quite high, ranging from 17.10-43.50% TAE. The leave extracts showed an interesting free radical scavenging activity and phenolic content as to be preconized for use instead of the roots. © Medwell Journal, 2010.
Authors & Co-Authors
Tibiri, André
Burkina Faso, Ouagadougou
Institut de Recherche en Sciences de la Santé
Sawadogo, Wamtinga Richard
Burkina Faso, Ouagadougou
Institut de Recherche en Sciences de la Santé
Ouédraogo, Noufou F.
Burkina Faso, Ouagadougou
Institut de Recherche en Sciences de la Santé
Banzouzi, Jean Théophile
Congo
Centre D'etude et de Recherche Médecins D'afrique Cerma
Guissou, Innocent Pierre
Burkina Faso, Ouagadougou
Institut de Recherche en Sciences de la Santé
Burkina Faso, Ouagadougou
University of Ouagadougou
Nacoulma, G. O.
Burkina Faso, Ouagadougou
University of Ouagadougou
Statistics
Citations: 34
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.3923/rjmsci.2010.81.87
ISSN:
18159346
e-ISSN:
19936095
Research Areas
Environmental