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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Liver ultrasound findings in a low prevalence area of S. japonicum in China: Comparison with history, physical examination, parasitological and serological results
Acta Tropica, Volume 51, No. 1, Year 1992
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Description
The paper describes a study carried out in a community in Dongdian township, Anhui Province, People's Republic of China. Medical history and the results of a physical examination, ultrasound investigation, parasitological and serological tests for Schistosoma japonicum infection were compared in 661 persons of 169 households. A lack of correlation between parasitological and serological indicators of infection and morbidity was observed in this area of low (6.4%) prevalence and intensity of infection. The prevalence of abnormal ultrasound findings in the liver in this population was high (56%), and was significantly higher than the prevalence of S. japonicum infection. The abnormal ultrasound findings correlated with a history of schistosomiasis, and the correlation increased significantly according to the number of times treated and the time since the last treatment, which suggested that past parenteral treatment has a role in the high rate of abnormal liver ultrasound findings. The significant correlation between the qualitative and quantitative serological results and abnormal ultrasound parenchymal patterns suggests that cross-reactivity between the etiology of the parenchymal disease and these tests is occurring. The presence of HBsAg correlated with the composite presence of ultrasound abnormalities of the liver parenchyma: increased echogenicity, periportal fibrosis and/or nodules and irregular fibrosis, whereas a normal ultrasound pattern was associated with the absence of HBV antigenemia. © 1992.
Authors & Co-Authors
Mott, Kenneth E.
Switzerland, Geneva
Organisation Mondiale de la Santé
Ming-Gang, Chen
Switzerland, Geneve
Parasitic Diseases Programme
Abdel-Wahab, Farid
Egypt, Giza
Cairo University
Burki, A.
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Dixon, Hubert G.
Switzerland, Geneva
Organisation Mondiale de la Santé
Fu-niu, Xu
China, Wuhu
Anhui Institute of Parasitic Diseases
Sen-hai, Yu
China, Beijing
Chinese Center for Disease Control and Prevention
Statistics
Citations: 15
Authors: 7
Affiliations: 6
Identifiers
Doi:
10.1016/0001-706X(92)90021-O
ISSN:
0001706X
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study
Study Approach
Qualitative
Quantitative