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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium
Translational Stroke Research, Volume 14, No. 4, Year 2023
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Description
Several studies have shown promising outcomes of the Woven EndoBridge (WEB) device for the treatment of wide-necked intracranial bifurcation aneurysms. This is a multicenter study attempts to explore the changes in trends and treatment outcomes over time for WEB embolization of intracranial aneurysms. The WorldWideWEB consortium is a retrospective multicenter collaboration of data from international centers spanning from January 2011 and June 2021, with no limitations on aneurysm location or rupture status. Both bifurcation and sidewall aneurysms were included. These patients were stratified based on treatment year into five treatment intervals: 2011–2015 (N = 66), 2016–2017 (N = 77), 2018 (N = 66), 2019 (N = 300), and 2020–2021 (N = 173). Patient characteristics and angiographic and clinical outcomes were compared between these time intervals. This study comprised 671 patients (median age 61.4 years; 71.2% female) with 682 intracranial aneurysms. Over time, we observed an increasing tendency to treat patients presenting with ruptured aneurysms and aneurysms with smaller neck, diameter, and dome widths. Furthermore, we observed a trend towards more off-label use of the WEB for sidewall aneurysms and increased adoption of transradial access for WEB deployment. Moreover, the proportion of patients with adequate WEB occlusion immediately and at last follow-up was significantly higher in more recent year cohorts, as well as lower rates of compaction and retreatment. Mortality and complications did not differ over time. This learning curve study suggests improved experience using the WEB for the treatment of intracranial aneurysms and has yielded higher rates of adequate occlusion over time. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Authors & Co-Authors
Dmytriw, Adam Andrew
Canada, London
London Health Sciences Centre
United States, Boston
Brigham and Women's Hospital
Dibas, Mahmoud
Canada, London
London Health Sciences Centre
Ghozy, Sherief A.
United States, Rochester
Mayo Clinic
Diestro, Jose Danilo Bengzon
Canada, Toronto
University of Toronto
Phan, Kevin
Australia, Melbourne
Austin Health
Sweid, Ahmad
United States, Philadelphia
Thomas Jefferson University
Renieri, Leonardo
Italy, Florence
Azienda Ospedaliera Careggi
Saliou, Guillaume
Switzerland, Lausanne
Centre Hospitalier Universitaire Vaudois
Möhlenbruch, Markus Alfred
Germany, Heidelberg
Universitätsklinikum Heidelberg
Regenhardt, Robert W.
United States, Boston
Brigham and Women's Hospital
Vranic, Justin E.
United States, Boston
Brigham and Women's Hospital
Waqas, Muhammad
United States, Buffalo
University at Buffalo, the State University of new York
Tutino, Vincent Matthew
United States, Buffalo
University at Buffalo, the State University of new York
Rabinov, James David
United States, Boston
Brigham and Women's Hospital
Piano, Mariangela G.
Italy, Milan
Asst Grande Ospedale Metropolitano Niguarda
Kühn, Anna Luisa
United States, Worcester
Umass Memorial Medical Center
Starke, Robert M.
United States, Coral Gables
University of Miami
Hassan, Ameer E.
Unknown Affiliation
Sporns, Peter B.
Germany, Hamburg
Universitätsklinikum Hamburg-eppendorf
Psychogios, Marios Nikos
Germany, Hamburg
Universitätsklinikum Hamburg-eppendorf
Spears, Julian
Canada, Toronto
University of Toronto
Panni, Pietro
Italy, Milan
Irccs Ospedale San Raffaele
Puri, Ajit S.
United States, Worcester
Umass Memorial Medical Center
Pero, Guglielmo Carlo
Italy, Milan
Asst Grande Ospedale Metropolitano Niguarda
Griessenauer, Christoph Johannes
United States, Danville
Geisinger
Austria, Salzburg
Paracelsus Medizinische Privatuniversitat
Asadi, Hamed
Australia, Melbourne
Austin Health
Stapleton, Christopher J.
United States, Boston
Brigham and Women's Hospital
Siddiqui, Adnan Hussain
United States, Buffalo
University at Buffalo, the State University of new York
Ducruet, A. F. F.
United States, Phoenix
Barrow Neurological Institute
Albuquerque, Felipe C.A.
United States, Phoenix
Barrow Neurological Institute
Du, Rose
United States, Boston
Brigham and Women's Hospital
Kan, Peter Tze Man
United States, Houston
Baylor College of Medicine
Lylyk, Pedro L.
Unknown Affiliation
Tjoumakaris, Stavropoula I.
United States, Philadelphia
Thomas Jefferson University
Ali Aziz-Sultan, Mohammad Ali
United States, Boston
Brigham and Women's Hospital
Jabbour, P. M.
United States, Philadelphia
Thomas Jefferson University
Cognard, Christophe H.
France, Toulouse
Chu de Toulouse
Patel, Aman B.
United States, Boston
Brigham and Women's Hospital
Statistics
Citations: 9
Authors: 38
Affiliations: 26
Identifiers
Doi:
10.1007/s12975-022-01072-x
ISSN:
18684483
Research Areas
Health System And Policy
Study Design
Cohort Study
Participants Gender
Female