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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Phenolic composition and biological activities of Tunisian Nigella sativa L. shoots and roots
Comptes Rendus - Biologies, Volume 331, No. 1, Year 2008
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Description
In the present investigation, methanolic extracts from shoots and roots of Tunisian Nigella sativa were assayed for their antioxidant and antimutagenic activities. The phenolic composition of the methanolic extracts was determined by RP-HPLC. The predominant phenolic compound was vanillic acid with a mean concentration of 143.21 and 89.94 mg per 100 g dry weight of shoots and roots, respectively. Shoots and roots showed comparable and strong superoxide scavenger activity; however, shoots exhibited higher DPPH radical scavenging, reducing and chelating activities than roots. Mutagenic and antimutagenic activities were determined by using the Ames test. Shoots and roots demonstrated important antimutagenic effects. Roots exhibited stronger activity than shoots with an inhibition percentage of 71.32%. To cite this article: S. Bourgou et al., C. R. Biologies 331 (2008). © 2007 Académie des sciences.
Authors & Co-Authors
Bourgou, Soumaya
Tunisia, Hamam Lif
Centre de Biotechnologie de Borj Cédria
Ksouri, Riadh
Tunisia, Hamam Lif
Centre de Biotechnologie de Borj Cédria
Bellila, Amor
Tunisia, Hamam Lif
Centre de Biotechnologie de Borj Cédria
Skandrani, Inès
Tunisia, Monastir
Faculté de Pharmacie de Monastir
Falleh, Hanen
Tunisia, Hamam Lif
Centre de Biotechnologie de Borj Cédria
Marzouk, Brahim
Tunisia, Hamam Lif
Centre de Biotechnologie de Borj Cédria
Statistics
Citations: 264
Authors: 6
Affiliations: 2
Identifiers
Doi:
10.1016/j.crvi.2007.11.001
ISSN:
16310691