Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Feline fecal virome reveals novel and prevalent enteric viruses
Veterinary Microbiology, Volume 171, No. 1-2, Year 2014
Notification
URL copied to clipboard!
Description
Humans keep more than 80 million cats worldwide, ensuring frequent exposure to their viruses. Despite such interactions the enteric virome of cats remains poorly understood. We analyzed a fecal sample from a single healthy cat from Portugal using viral metagenomics and detected five eukaryotic viral genomes. These viruses included a novel picornavirus (proposed genus "Sakobuvirus") and bocavirus (feline bocavirus 2), a variant of feline astrovirus 2 and sequence fragments of a highly divergent feline rotavirus and picobirnavirus. Feline sakobuvirus A represents the prototype species of a proposed new genus in the Picornaviridae family, distantly related to human salivirus and kobuvirus. Feline astroviruses (mamastrovirus 2) are the closest known relatives of the classic human astroviruses (mamastrovirus 1), suggestive of past cross-species transmission. Presence of these viruses by PCR among Portuguese cats was detected in 13% (rotavirus), 7% (astrovirus), 6% (bocavirus), 4% (sakobuvirus), and 4% (picobirnavirus) of 55 feline fecal samples. Co-infections were frequent with 40% (4/10) of infected cats shedding more than one of these five viruses. Our study provides an initial description of the feline fecal virome indicating a high level of asymptomatic infections. Availability of the genome sequences of these viruses will facilitate future tropism and feline disease association studies. © 2014 Elsevier B.V.
Authors & Co-Authors
Ng, Terry Fei Fan
United States, San Francisco
Vitalant Research Institute
United States, San Francisco
University of California, San Francisco
Mesquita, João R.
Portugal, Viseu
Instituto Politécnico de Viseu
Nascimento, M. S.J.
Portugal, Porto
Universidade do Porto
Kondov, Nikola O.
United States, San Francisco
Vitalant Research Institute
Wong, Walt
United States, San Francisco
Vitalant Research Institute
Reuter, Gábor
Hungary, Pecs
Pécsi Tudományegyetem
Knowles, Nick James
United Kingdom, Surrey
The Pirbright Institute
Vega, Everardo M.
United States, Atlanta
Centers for Disease Control and Prevention
Esona, Mathew Dioh
United States, Atlanta
Centers for Disease Control and Prevention
Deng, Xutao
United States, San Francisco
Vitalant Research Institute
United States, San Francisco
University of California, San Francisco
Vinjé, Jan
United States, Atlanta
Centers for Disease Control and Prevention
Delwart, E. L.
United States, San Francisco
Vitalant Research Institute
United States, San Francisco
University of California, San Francisco
Statistics
Citations: 77
Authors: 12
Affiliations: 7
Identifiers
Doi:
10.1016/j.vetmic.2014.04.005
ISSN:
03781135