Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Lipids and lipoprotein(a) concentrations in Tunisian type 2 diabetic patients: Relationship to glycemic control and coronary heart disease
Journal of Diabetes and its Complications, Volume 18, No. 5, Year 2004
Notification
URL copied to clipboard!
Description
The aim of this study was to evaluate plasma lipoprotein(a) [Lp(a)] concentrations in Tunisian patients with type 2 diabetes mellitus (DM), to correlate the values with other lipid parameters, and to examine the relationship to glycemic control and coronary heart disease (CHD). Diabetic patients with and without CHD (n=200) had significantly higher levels of Lp(a) (327.94±239.93 mg/l) and a greater proportion of elevated (>300 mg/l) Lp(a) concentrations (46%) compared with 100 healthy nondiabetic controls (269.83±225.6 mg/l, P<.01, and 26%, P<.01), while there were no statistically significant difference between diabetics without CHD (n=100) and controls. No significant association of Lp(a) with glycemic control (HbAlc or fasting blood glucose) was noted in diabetic patients. Positive correlations were observed between Lp(a) levels and total cholesterol and LDL-C in all diabetic patients and particularly in diabetic men. Male patients with CHD showed significantly higher plasma Lp(a) levels than those without CHD (P=.023), and 57.3% of patients with CHD showed increase (>300 mg/l) Lp(a) compared with 33.3% of patients without CHD. Elevated levels of Lp (a) and abnormal lipid profile in diabetic men suggest their involvement in atherogenesis and subsequent development of CHD. © 2004 Elsevier Inc. All rights reserved.
Authors & Co-Authors
Smaoui, Maha
Tunisia, Monastir
Faculté de Médecine de Monastir
Hammami, Sonia Ouali
Tunisia, Monastir
Chu Fattouma-bourguiba
Châaba, Raja
Tunisia, Monastir
Faculté de Médecine de Monastir
Attia, Nebil
Tunisia, Monastir
Faculté de Médecine de Monastir
Hamda, Khaldoun Ben
Tunisia, Monastir
Chu Fattouma-bourguiba
Masmoudi, Ahmed Slaheddine
Tunisia, Monastir
Faculté de Médecine de Monastir
Mahjoub, Sylvia S.
Tunisia, Monastir
Chu Fattouma-bourguiba
Bousslama, Ali
Tunisia, Sousse
Chu Sahloul
Farhat, Mohamed Ben
Tunisia, Monastir
Chu Fattouma-bourguiba
Hammami, M. B.
Tunisia, Monastir
Faculté de Médecine de Monastir
Statistics
Citations: 10
Authors: 10
Affiliations: 3
Identifiers
Doi:
10.1016/S1056-8727(03)00075-8
ISSN:
10568727
Research Areas
Noncommunicable Diseases
Participants Gender
Male