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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Assessment of myocardial perfusion during adenosine stress using real time three-dimensional and two-dimensional myocardial contrast echocardiography: Comparison with single-photon emission computed tomography
Echocardiography, Volume 27, No. 4, Year 2010
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Description
Objectives: To evaluate diagnostic accuracy of adenosine two-dimensional and three-dimensional myocardial contrast echocardiography (2D- and 3D-MCE) compared with single-photon emission computed tomography (SPECT) for assessing myocardial perfusion. Methods: From January through August 2007, patients with known or suspected CAD who were referred for SPECT underwent simultaneous adenosine 2D-MCE and 3D-MCE (live and full volume FV). Perfusion and wall motion in 17 segments in the left anterior descending, left circumflex, and right coronary artery territories were analyzed. Results: We studied 30 patients: mean (SD) age, 72.6 (8.2) years; 19 (63%) men. Perfusion by SPECT was abnormal in 13 patients (43%). When comparing MCE with SPECT, sensitivity was comparable for 2D-MCE, 92%; live 3D-MCE, 91%; and FV 3D-MCE, 90%. Specificity was comparable for 2D-MCE, 75%; live 3D-MCE, 69%; and FV 3D-MCE, 79%. Agreement between live 3D-MCE and 2D-MCE was 92% (κSE, 0.83 0.17) and between FV 3D-MCE and 2D-MCE, 88% (κSE, 0.76 0.13). For eight patients in whom SPECT showed reversible defects, live 3D-MCE correctly identified defects in seven (88%), whereas FV 3D-MCE correctly identified them in five (63%) (P = 0.57). Conclusion: Myocardial perfusion assessment is feasible by 3D-MCE with the advantage of rapid, facile acquisition and offline image manipulation. (Echocardiography 2010;27:421-429) © 2010, Wiley Periodicals, Inc.
Authors & Co-Authors
Abdelmoneim, Sahar S.
United States, Rochester
Mayo Clinic
Egypt, Asyut
Assiut University
Bernier, Mathieu
United States, Rochester
Mayo Clinic
Dhoble, Abhijeet
United States, Rochester
Mayo Clinic
Moir, Stuart
United States, Rochester
Mayo Clinic
Hagen, Mary E.
United States, Rochester
Mayo Clinic
Ness, Sue Ann C.
United States, Rochester
Mayo Clinic
Abdel-Kader, Samir S.
Egypt, Asyut
Assiut University
Pellikka, Patricia A.
United States, Rochester
Mayo Clinic
Mulvagh, Sharon L.
United States, Rochester
Mayo Clinic
Statistics
Citations: 18
Authors: 9
Affiliations: 2
Identifiers
Doi:
10.1111/j.1540-8175.2009.01026.x
ISSN:
07422822
e-ISSN:
15408175
Research Areas
Environmental
Participants Gender
Male