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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prevalence of proteinuria among HIV-infected children attending a tertiary hospital in Lagos, Nigeria
Journal of Tropical Pediatrics, Volume 56, No. 3, Article fmp090, Year 2009
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Description
Sub-Saharan Africa is the epicentre of the HIV pandemic but there are few reports of HIV-related kidney diseases in children in this region. This study aimed to determine the prevalence of proteinuria in HIV-infected children at the Lagos University Teaching Hospital. Proteinuria was determined using urine protein-creatinine ratio. CD4+ cell count was determined for all the HIV-infected children. The mean age of the HIV-infected children was 74.4 ± 35.6 months with a male: female ratio of 3:2. Compared with 6% of the 50 controls 20.5% of the 88 HIV-infected children had proteinuria (p = 0.026). Of 20 children with advanced clinical stage 40% had proteinuria compared with 14.7% of 68 children with milder stage (p = 0.004). Similarly, proteinuria was commoner among those with severe immunosuppression (p = 0.014). HAART use was not associated with significant difference in proteinuria prevalence (p = 0.491). Proteinuria was frequent among HIV-infected children, especially among those with advanced disease. © The Author [2009]. Published by Oxford University Press. All rights reserved.
Authors & Co-Authors
Esezobor, C. I.
Nigeria, Lagos
Lagos University Teaching Hospital
Iroha, Edna O.
Nigeria, Lagos
Lagos University Teaching Hospital
Onifade, Elizabeth Urowayino
United Kingdom, Northallerton
Friarage Hospital
Akinsulie, Adebola Olumide
Nigeria, Lagos
Lagos University Teaching Hospital
Temiye, Edamisan Olusoji
Nigeria, Lagos
Lagos University Teaching Hospital
Ezeaka, Veronica Chinyere
Nigeria, Lagos
Lagos University Teaching Hospital
Statistics
Citations: 37
Authors: 6
Affiliations: 2
Identifiers
Doi:
10.1093/tropej/fmp090
ISSN:
01426338
e-ISSN:
14653664
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Study Locations
Nigeria
Participants Gender
Male
Female