Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0
HIV Medicine, Volume 21, No. 10, Year 2020
Notification
URL copied to clipboard!
Description
Background: The European AIDS Clinical Society (EACS) Guidelines cover key aspects of HIV management with major updates every two years. Guideline highlights: The 2019 Guidelines were extended with a new section focusing on drug–drug interactions and other prescribing issues in people living with HIV (PLWH). The recommendations for treatment-naïve PLWH were updated with four preferred regimens favouring unboosted integrase inhibitors. A two-drug regimen with dolutegravir and lamivudine, and a three-drug regimen including doravirine were also added to the recommended initial regimens. Lower thresholds for hypertension were expanded to all PLWH and for cardiovascular disease prevention, the 10-year predicted risk threshold for consideration of antiretroviral therapy (ART) modification was lowered from 20% to 10%. Frailty and obesity were added as new topics. It was specified to use urine albumin to creatinine ratio to screen for glomerular disease and urine protein to creatinine ratio for tubular diseases, and thresholds were streamlined with the Kidney Disease: Improving Global Outcomes (KDIGO) recommendations. Hepatitis C virus (HCV) treatment recommendations were split into preferred and alternative treatment options. The algorithm for management of recently acquired HCV infection was updated and includes recommendations for early chronic infection management. Treatment of resistant tuberculosis (TB) was streamlined with the World Health Organization (WHO) recommendations, and new tables on immune reconstitution inflammatory syndrome, on when to start ART in the presence of opportunistic infections and on TB drug dosing were included. Conclusions: The EACS Guidelines underwent major revisions of all sections in 2019. They are available in four different formats including a new interactive web-based version and are translated into Chinese, French, German, Japanese, Portuguese, Russian and Spanish. © 2020 The Authors. HIV Medicine published by John Wiley & Sons Ltd on behalf of British HIV Association
Authors & Co-Authors
Ryom, Lene
Denmark, Copenhagen
Københavns Universitet
Cotter, Aoife Grace
Ireland, Dublin
University College Dublin
Arribas, Jose R.
Spain, Madrid
Hospital Universitario la Paz
Marzolini, Catia
Switzerland, Basel
Universitat Basel
United Kingdom, Liverpool
University of Liverpool
Mallon, Patrick W.G.
Ireland, Dublin
University College Dublin
Rauch, Andri
Switzerland, Bern
University of Bern
Kirk, Ole
Denmark, Copenhagen
Københavns Universitet
Molina, Jean Michel
France, Paris
Ap-hp Assistance Publique - Hopitaux de Paris
Guaraldi, Giovanni
Italy, Modena
Università Degli Studi Di Modena e Reggio Emilia
Winston, Alan
United Kingdom, London
Imperial College London
Bhagani, Sanjay R.
United Kingdom, London
Royal Free London Nhs Foundation Trust
Cinque, P.
Italy, Milan
Irccs Ospedale San Raffaele
Kowalska, Justyna Dominika
Poland, Warsaw
Medical University of Warsaw
Collins, Simon
United Kingdom, London
Hiv I-base
Battegay, Manuel
Switzerland, Basel
Universitat Basel
D'Arminio Monforte, Antonella D.
Unknown Affiliation
Dedes, Nikos
Unknown Affiliation
Horban, Andrzéj
Unknown Affiliation
Katlama, Christine
Unknown Affiliation
McCormack, Sheena Mary G.
Unknown Affiliation
Mussini, Cristina
Unknown Affiliation
Pozniak, Anton L.
Unknown Affiliation
Pulido, F.
Unknown Affiliation
Raffi, François
Unknown Affiliation
Stellbrink, Hans Jürgen
Unknown Affiliation
Vasylyev, Marta
Unknown Affiliation
Gibbons, Sara E.
Unknown Affiliation
Bower, Mark D.
Unknown Affiliation
Compston, Juliette Elizabeth
Unknown Affiliation
de Wit, Stéphane
Unknown Affiliation
Fabbri, Leonardo M.
Unknown Affiliation
Fux, Christoph Andreas
Unknown Affiliation
Gisslèn, Magnus
Unknown Affiliation
Lundgren, Jens D.
Unknown Affiliation
Miró, José Mª
Unknown Affiliation
Poulter, Neil R.
Unknown Affiliation
Sebastiani, Giada
Unknown Affiliation
Berenguer, Juan J.
Unknown Affiliation
Boesecke, Christoph
Unknown Affiliation
Bruno, R.
Unknown Affiliation
Lacombe, Karine
Unknown Affiliation
Mendão, Luís
Unknown Affiliation
Peters, Lars
Unknown Affiliation
Puoti, Massimo
Unknown Affiliation
Ambrosioni, Juan C.
Unknown Affiliation
de Castro, Nathalie
Unknown Affiliation
Fätkenheuer, Gerd
Unknown Affiliation
Furrer, Hansjakob Jackob
Unknown Affiliation
Oprea, Cristiana
Unknown Affiliation
Volny-Anne, Alain
Unknown Affiliation
Mulcahy, Fiona M.
Unknown Affiliation
Wensing, Annemarie Marie J.
Unknown Affiliation
Statistics
Citations: 110
Authors: 52
Affiliations: 13
Identifiers
Doi:
10.1111/hiv.12878
ISSN:
14642662
Research Areas
Health System And Policy
Infectious Diseases
Noncommunicable Diseases