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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Induced protein polymorphisms and nutritional quality of gamma irradiation mutants of sorghum
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, Volume 749, No. 1-2, Year 2013
Notification
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Description
Physical and biochemical analysis of protein polymorphisms in seed storage proteins of a mutant population of sorghum revealed a mutant with redirected accumulation of kafirin proteins in the germ. The change in storage proteins was accompanied by an unusually high level accumulation of free lysine and other essential amino acids in the endosperm. This mutant further displayed a significant suppression in the synthesis and accumulation of the 27. kDa γ-, 24. kDa α-A1 and the 22. kDa α-A2 kafirins in the endosperm. The suppression of kafirins was counteracted by an upsurge in the synthesis and accumulation of albumins, globulins and other proteins. The data collectively suggest that sorghum has huge genetic potential for nutritional biofortification and that induced mutations can be used as an effective tool in achieving premium nutrition in staple cereals. © 2013 .
Authors & Co-Authors
Mehlo, Luke
South Africa, Pretoria
The Council for Scientific and Industrial Research
Mbambo, Zodwa
South Africa, Pretoria
The Council for Scientific and Industrial Research
South Africa, Durban
University of Kwazulu-natal
Bado, Souleymane
Austria, Vienna
International Atomic Energy Agency, Vienna
Lin, Johnson
South Africa, Durban
University of Kwazulu-natal
Moagi, Sydwell M.
South Africa, Pretoria
The Council for Scientific and Industrial Research
Buthelezi, Sindisiwe G.
South Africa, Pretoria
The Council for Scientific and Industrial Research
Stoychev, Stoyan H.
South Africa, Pretoria
The Council for Scientific and Industrial Research
Chikwamba, Rachel K.
South Africa, Pretoria
The Council for Scientific and Industrial Research
Statistics
Citations: 31
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.1016/j.mrfmmm.2013.05.002
ISSN:
00275107
e-ISSN:
09218262
Research Areas
Food Security
Genetics And Genomics
Study Design
Cross Sectional Study