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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Natural anti-inflammatory products and leukotriene inhibitors as complementary therapy for bronchial asthma
Clinical Biochemistry, Volume 43, No. 10-11, Year 2010
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Description
ObjectiveTo assess the efficacy of a combination of Boswellia serrata, licorice root (Glycyrrhiza glabra) and Tumeric root (Curcuma longa) as natural leukotriene inhibitor, antiinflammatory and antioxidant products respectively in controlling bronchial asthma. Subjects and methodsThe study comprised 63 patients with bronchial asthma that are further subdivided into two groups .Group 1 receiving oral capsule (combined herb) in a soft-gelatin capsule 3 times daily for 4. weeks and group 2 receiving placebo.Plasma leukotriene C4 (LTC4), nitric oxide (NO) and malondialdehyde (MDA) levels were measured and pulmonary function was also assessed in all patients enrolled in the study. Results: There was a statistically significant decrease in the plasma levels of LTC4, (MDA), and NO in target therapy group when compared with placebo group. Conclusion: The used extract contained Boswellia serrata, Curcuma longa and Glycyrrhiza has a pronounced effect in the management of bronchial asthma. © 2010 The Canadian Society of Clinical Chemists.
Authors & Co-Authors
Houssen, Maha E.
Egypt, Beni Suef
Faculty of Pharmacy
Ragab, Amany
Egypt, Mansoura
Faculty of Medicine
Mesbah, Abeer
Egypt, Mansoura
Faculty of Medicine
El Samanoudy, A.
Egypt, Mansoura
Faculty of Medicine
Othman, Gamal
Egypt, Mansoura
Faculty of Medicine
Fathy, A.
Egypt, Mansoura
Faculty of Medicine
Badria, Farid A.
Egypt, Mansoura
Mansoura University
Statistics
Citations: 61
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/j.clinbiochem.2010.04.061
Research Areas
Health System And Policy