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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Parameters predicting outcomes of strabismus surgery in the management of Graves' ophthalmopathy
Journal of AAPOS, Volume 13, No. 3, Year 2009
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Description
Background: Ocular dysmotility is a common feature of Graves' ophthalmopathy and frequently requires strabismus surgery. We reviewed the short-term results of strabismus surgery for Graves' ophthalmopathy to determine pre- and perioperative parameters predictive of postoperative outcome. Methods: A retrospective review of Graves' ophthalmopathy patients who underwent strabismus surgery. Outcomes were correlated with preoperative and operative characteristics. The main outcome measure was field of binocular single vision score. Residual postoperative strabismus was considered a secondary outcome. Preoperative characteristics examined included age and laterality at onset, sex, disease activity, smoking status, and treatment for Graves' ophthalmopathy. Good outcome was defined as field of binocular single vision >50% and heterophoria in the primary position. Moderate outcome was defined as a field of binocular single vision 1% to 50% with heterotropia but with correctable diplopia in the primary position using prisms or head tilt. Poor outcome was defined as no measurable field of binocular single vision and intractable diplopia. Results: Fifty patients were identified: 28 women, 22 men; mean age, 54 years (SD ± 12.8). Thirty-seven (74%) had good and 13 (26%) had moderate or poor outcomes. Preoperative characteristics that were associated with good outcomes were symmetry of orbitopathy at Graves' ophthalmopathy onset (χ2 = 7.5, p = 0.001) and earlier timing of surgery (t = -2.9, p = 0.003). Conclusion: Relative symmetry of orbitopathy at onset and a shorter time interval between onset of orbitopathy and surgery, while allowing for disease stability, are predictive of a good outcome following strabismus surgery for Graves' ophthalmopathy.{A figure is presented}. © 2009 American Association for Pediatric Ophthalmology and Strabismus.
Authors & Co-Authors
Nassar, Mahmoud Mamdouh
United Kingdom, Newcastle
Royal Victoria Infirmary
Dickinson, A. Jane
United Kingdom, Newcastle
Royal Victoria Infirmary
Neoh, Christopher
United Kingdom, Newcastle
Royal Victoria Infirmary
Powell, Christine
United Kingdom, Newcastle
Royal Victoria Infirmary
Buck, Deborah
United Kingdom, Newcastle
Newcastle University
Galal, Ezzeldin
Egypt, Minya
Al-minya University Hospital
Clarke, Michael P.
United Kingdom, Newcastle
Newcastle University
Statistics
Citations: 34
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/j.jaapos.2008.11.007
ISSN:
10918531
Research Areas
Health System And Policy
Study Design
Cohort Study
Participants Gender
Male
Female