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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Pyrazolopyranopyrimidines as a class of anti-inflammatory agents
Zeitschrift fur Naturforschung - Section C Journal of Biosciences, Volume 61, No. 1-2, Year 2006
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Description
Pyrazolopyranopyrimidines 6a-c and 8a-c were prepared from the reaction of compounds 4a-c or 7a-c with methylamine or ammonium hydroxide solutions. Treatment of compounds 6a-c or 8a-c with 2-chloroethyl methyl ether afforded their corresponding acyclonucleosides 9a-c or 10a-c, respectively, as a new class of acyclonucleosides. All prepared compounds were tested as anti-inflammatory agents and some of them revealed moderate to potent anti-inflammatory activity. © 2005 Verlag der Zeitschrift für Naturforschung.
Authors & Co-Authors
Zaki, Magdi E.A.
Egypt, Giza
National Research Centre
Soliman, Hanan A.
Egypt, Giza
National Research Centre
Heikal, Ola Ahmed
Egypt, New Cairo
German University in Cairo
Rashad, Aymn E.
Egypt, Giza
National Research Centre
Statistics
Citations: 237
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1515/znc-2006-1-201
ISSN:
09395075