Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
216 cases of pancreaticoduodenectomy: Risk factors for postoperative complications
Hepato-Gastroenterology, Volume 55, No. 84, Year 2008
Notification
URL copied to clipboard!
Description
Background/Aims: Surgical resection remains the best treatment for patients with periampullary tumors. Many series have been reported with low or zero mortality, however, high incidence of complications is the rule. This study aims to present the results of pancreaticoduodenectomy and factors predisposing to postoperative complications, especially pancreatic leak, at our center. Methodology: Between January 2000 and December 2006, 216 periampullary tumors were treated by Whipple pancreaticoduodenectomy. Pancreaticogastrostomy was done in 183 patients and pancreaticojejunostomy in 33 patients. Hospital mortality and surgical complications were recorded with special emphasis on pancreatic leak. All specimens were histologically examined for the presence and origin of malignant tissue. Results: The mean age was 58 years and male to female ratio was 2:1. The commonest symptom was jaundice (97.7%) followed by abdominal pain (74%). Operative mortality in 7 patients (3.2%). 71 (33%) patients developed 1 or more complications. pancreatic leak occurred in 23 (10.6%) patients, abdominal collection in 23 patients (10.6%) and delayed gastric emptying in 19 (8.8%) patients. Factors that influenced the development of postoperative complications included type of pancreaticoenteric anastomosis, pancreatic texture and intraoperative blood transfusion of 4 or more blood units. Pancreatic leak was commoner with PJ (p=0.001), soft pancreatic texture (p=0.008), intraoperative blood transfusion of 4 or more units (p<0.0001). Periampullary adenocarcinoma was found in 204 (94.4%) patients, chronic pancreatitis in 9 (4.2%) patients, 2 patients with solid and papillary neoplasm, and 1 patient with NHL (Non-Hodgkin's Lymphoma). Conclusions: Surgery is the only hope for patients with periampullary tumors. Postoperative complications after pancreaticoduodenectomy depend largely on surgical technique and can be reduced reasonably with the adoption of pancreaticogastrostomy, which is safer and easier to learn than pancreaticojejunostomy. © H.G.E. Update Medical Publishing S.A.
Authors & Co-Authors
Fathy, Omar Mohammed
Egypt, Mansoura
Gastrointestinal Surgery Center
Abd Elwahab, M. M.
Egypt, Mansoura
Gastrointestinal Surgery Center
Elghwalby, N.
Egypt, Mansoura
Gastrointestinal Surgery Center
Sultan, Ahmed
Egypt, Mansoura
Gastrointestinal Surgery Center
El-Ebidy, Gamal
Egypt, Mansoura
Gastrointestinal Surgery Center
GadEl Hak, Nabil
Egypt, Mansoura
Gastrointestinal Surgery Center
Abu Zeid, Mostafa S.O.
Egypt, Mansoura
Gastrointestinal Surgery Center
Abd-Allah, T.
Egypt, Mansoura
Gastrointestinal Surgery Center
El- Shobary, Mohamed
Egypt, Mansoura
Gastrointestinal Surgery Center
Fouad, Amgad A.
Egypt, Mansoura
Gastrointestinal Surgery Center
Kandeel, T.
Egypt, Mansoura
Gastrointestinal Surgery Center
Abo Elenien, A.
Egypt, Mansoura
Gastrointestinal Surgery Center
Abd El-Raouf, Ahmed
Egypt, Mansoura
Gastrointestinal Surgery Center
Hamdy, Emad
Egypt, Mansoura
Gastrointestinal Surgery Center
Ezzat, Farouk A.
Egypt, Mansoura
Gastrointestinal Surgery Center
Statistics
Citations: 15
Authors: 15
Affiliations: 1
Research Areas
Cancer
Health System And Policy
Study Design
Cohort Study
Participants Gender
Male
Female