Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Thyroid malignancy in endemic nodular goitres: Prevalence, pattern and treatment
European Journal of Surgical Oncology, Volume 27, No. 2, Year 2001
Notification
URL copied to clipboard!
Description
Aims: The epidemiology of thyroid cancers in goitre endemic zones has not been recently reviewed, and changes being currently reported have been from studies in non-endemic areas. The aims of this study were to present the clinical pattern of thyroid malignancy in a goitre endemic area and identify recent changes, if any. Methods: The study was conducted at Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria between January 1983 and December 1993. Records of patients with nodular goitres treated with thyroidectomy were reviewed, and the clinical features, laboratory parameters, treatment, outcome and follow-up of histologically-proven malignant cases were studied. Results: Thirty-six of 279 (12.9%) patients, aged 13-85 years (mean) = 43.7 ± 14.7 years), carried malignant goitres, and most (80%) were young or middle-aged women. Of the well-differentiated cancers, follicular type was the most prevalent, being six- and 12-fold as frequent as papillary and medullary cancers (69% vs 11% and 5.6%), respectively. Lymphoma accounted for 5.6%, fibrosarcoma, 5.6% and anaplastic, 2.8%. No relationship was demonstrable between cancer type, duration of goitre and age at diagnosis (r=0.06 and 0.17, respectively). Conclusions: Thyroid cancer afflict comparatively young women in our environment, and follicular cancer remains the predominant type, partly as a result of persisting dietary iodine deficiency. © 2001 Harcourt Publishers Ltd.
Authors & Co-Authors
Lawal, Olukayode O.
Nigeria, Ife
Obafemi Awolowo University
Agbakwuru, E. A.
Nigeria, Ife
Obafemi Awolowo University
Olayinka, O. S.
Nigeria, Ife
Obafemi Awolowo University
Adelusola, Kayode Adebowale
Nigeria, Ife
Obafemi Awolowo University
Statistics
Citations: 48
Authors: 4
Affiliations: 1
Identifiers
Doi:
10.1053/ejso.2000.1085
ISSN:
07487983
Research Areas
Cancer
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Nigeria
Participants Gender
Female