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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
A peer-education intervention to reduce injection risk behaviors for HIV and hepatitis C virus infection in young injection drug users
AIDS, Volume 21, No. 14, Year 2007
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Description
OBJECTIVES: To evaluate whether a behavioral intervention, which taught peer education skills, could reduce injection and sexual risk behaviors associated with primary HIV and hepatitis C virus infection (HCV) among young injection drug users (IDU). DESIGN: We conducted a randomized controlled trial involving HIV and HCV antibody-negative IDU, aged 15-30 years, recruited in five United States cities. A six-session, small-group, cognitive behavioral, skills-building intervention in which participants were taught peer education skills (n = 431) was compared with a time-equivalent attention control (n = 423). Baseline visits included interviews for sociodemographic, psychosocial, and behavioral factors during the previous 3 months; HIV and HCV antibody testing; and pre/posttest counselling. Procedures were repeated 3 and 6 months postintervention. RESULTS: The intervention produced a 29% greater decline in overall injection risk 6 months postintervention relative to the control [proportional odds ratio 0.71; 95% confidence limit (CL) 0.52, 0.97], and a 76% decrease compared with baseline. Decreases were also observed for sexual risk behaviors, but they did not differ by trial arm. Overall HCV infection incidence (18.4/100 person-years) did not differ significantly across trial arms (relative risk 1.15; 95% CL 0.72, 1.82). No HIV seroconversions were observed. CONCLUSION: Interventions providing information, enhancing risk-reduction skills, and motivating behavior change through peer education training can reduce injection risk behaviors, although risk elimination might be necessary to prevent HCV transmission. © 2007 Lippincott Williams & Wilkins, Inc.
Authors & Co-Authors
Garfein, Richard S.
United States, Atlanta
Centers for Disease Control and Prevention
United States, La Jolla
University of California, San Diego
Golub, Elizabeth Topper
United States, Baltimore
Johns Hopkins University
Greenberg, Alan E.
United States, Atlanta
Centers for Disease Control and Prevention
United States, Washington, D.c.
Milken Institute School of Public Health
Hagan, Holly C.
Unknown Affiliation
Hanson, Debra L.
United States, Atlanta
Centers for Disease Control and Prevention
Hudson, Sharon M.
United States
Health Research Association
Kapadia, Farzana
United States, New York
New York Academy of Medicine
Latka, Mary H.
United States, New York
New York Academy of Medicine
Ouellet, Lawrence J.
United States, Chicago
University of Illinois at Chicago
Purcell, David W.
United States, Atlanta
Centers for Disease Control and Prevention
Strathdee, Steffanie Anne
United States, La Jolla
University of California, San Diego
Thiede, Hanne
United States, Seattle
Seattle King County Department of Public Health
Statistics
Citations: 157
Authors: 12
Affiliations: 8
Identifiers
Doi:
10.1097/QAD.0b013e32823f9066
ISSN:
02699370
Research Areas
Infectious Diseases
Sexual And Reproductive Health
Study Design
Randomised Control Trial
Cohort Study
Case-Control Study
Study Approach
Quantitative