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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
What happens to people diagnosed with tuberculosis? A population-based cohort
Epidemiology and Infection, Volume 135, No. 7, Year 2007
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Description
We examined different patient outcomes following diagnosis of tuberculosis (TB). Incident cases were reported to the enhanced surveillance system in the East of England, between 2000 and 2003. For the 575 cases reported in 2001 and 2002, outcomes were assessed 1 year after initiating treatment. The crude clinical incidence rate of TB was 6.0 cases/100 000 person-years (pyr) [95% confidence interval (CI) 5.7-6.4], highest in the 25-29 years age group (14.9, 95% CI 12.9-17.1 cases/100 000 pyr) and among Black Africans (328.6, 95% CI 286.9-374 cases/100 000 pyr). Patients born abroad were 2.35 (95% CI 1.03-5.32) times more likely to be lost to follow-up than those born in the United Kingdom. Age at diagnosis (OR 1.05, 95% CI 1.04-1.07) and pulmonary disease (OR 2.73, 95% CI 1.21-6.15) were independently associated with mortality. Elderly patients and those with pulmonary TB appear to have worse outcomes despite treatment. Foreign-born patients may need closer follow-up to ensure favourable outcomes. © 2007 Cambridge University Press.
Authors & Co-Authors
Anyama, Norbert G.
Uganda, Kampala
Makerere University
Bracebridge, Samantha
United Kingdom, London
Public Health England
Black, C.
United Kingdom, London
Public Health England
Niggebrugge, A.
United Kingdom, Cambridge
Eastern Region Public Health Observatory
Griffin, Simon J.
United Kingdom, Cambridge
Strangeways Research Laboratory
Statistics
Citations: 11
Authors: 5
Affiliations: 4
Identifiers
Doi:
10.1017/S0950268807007996
ISSN:
09502688
e-ISSN:
14694409
Research Areas
Health System And Policy
Infectious Diseases
Study Design
Cross Sectional Study
Cohort Study