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AFRICAN RESEARCH NEXUS

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medicine

Antinociceptive activity of Zizyphus spina-christi root bark extract

Fitoterapia, Volume 72, No. 4, Year 2001

The antinociceptive effect of the aqueous extract of Zizyphus spina-christi root bark was investigated in mice and rats. Acetic acid-induced writhing, formalin and thermal (hot plate) tests were used. The extract (50 and 100 mg/kg, i.p.) showed a dose-dependent analgesic effect in all the tests used. Its i.p. LD50 in mice was 2236.07 mg/kg. Copyright © 2001 Elsevier Science B.V.

Statistics
Citations: 151
Authors: 4
Affiliations: 1
Identifiers
Doi: 10.1016/S0367-326X(00)00289-6
ISSN: 0367326X

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