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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Ethiopian visceral leishmaniasis patients co-infected with human immunodeficiency virus
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 89, No. 2, Year 1995
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Description
This communication reports 7 Ethiopian visceral leishmaniasis (VL) patients co-infected with human immunodeficiency virus (HIV). The clinical and laboratory findings in 6 patients did not differ from classical VL. All patients had highly elevated anti-leishmanial antibody titres, determined by immunoglobulin G-based enzyme-linked immunosorbent assay; they most probably acquired the Leishmania infection before HIV. Amastigotes were identified in the splenic aspirates of 6 patients and in the lymph node aspirate of the 2 patients whose lymph nodes were examined. The CD4:CD8 lymphocyte ratio was depressed in those patients whose ratio was determined. Most patients showed some initial response to pentavalent antimonial therapy. © 1995 Oxford University Press.
Authors & Co-Authors
Bethel, Nega
Ethiopia, Addis Ababa
Addis Ababa University
Hailu, Asrat
Ethiopia, Addis Ababa
Addis Ababa University
Wolday, Dawit
Ethiopia, Addis Ababa
Addis Ababa University
Negesse, Yohannes
Ethiopia, Addis Ababa
Armed Forces General Hospital Addis Ababa
Cenini, Pietro
Ethiopia, Addis Ababa
Armauer Hansen Research Institute
Frommel, Dominique
Ethiopia, Addis Ababa
Armauer Hansen Research Institute
Statistics
Citations: 36
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1016/0035-9203(95)90497-2
ISSN:
00359203
e-ISSN:
18783503
Research Areas
Infectious Diseases