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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Characteristics and results of the treatment of multiple myeloma in the subject under the age of 65 at the University Hospital of Yopougon in Abidjan, Côte d'Ivoire
Advances in Hematology, Volume 2013, Article 583051, Year 2013
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Description
We retrospectively studied 30 cases of multiple myeloma in patients under the age of 65, diagnosed from 1991 to 2005 in the clinical hematology department of the University Hospital of Yopougon that is a hospital incidence of 2.9 cases/year. The age of patients ranged from 34 to 64 years, with a mean age of 49 years and a sex ratio of 1.73. The professional activity was variable with 3% of radiographers and 10% of farmers. Clinically, the dominant sign was bone pain in 83% of cases. Myeloma was secretory in 93% of cases. It was Ig G-type in 86%, kappa-type in 66% of cases. 86% of patients were anemic, 20% had creatinine >20 mg/L, and 10% had serum calcium >120 mg/L. Geodes were found in 80% of cases. 53% were at stage III of DURIE and SALMON. Complications were infectious (33%), renal (20%), and hemorrhagic (7%). Chemotherapy regimens were VAD (10%), VMCP (30%), and VMCP/VBAP (60%) with 47% of partial responses, 33% of stable disease, and 7% of very good quality partial responses. The outcome developed towards death in 37% and causes of death were renal in 46% of cases. The median survival was only 5.1 months. © 2013 Diebkilé Aïssata Tolo et al.
Authors & Co-Authors
Aïssata, Tolo Diebkilé
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Sawadogo, Duni
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Nanho, Danho Clotaire
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Kouakou, Boidy
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Méité, N'Dogomo D.
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Ayémou, Roméo
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Kouéhion, Paul
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Mozart, Konan
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Sékongo, Yassongui Mamadou
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
N'Dhatz, Emeraude
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Kamara, Ismaël
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Silué, Dohoma Alexis
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Koffi, Kouassi Gustave
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Sanogo, Ibrahima
Cote D'ivoire, Abidjan
Teaching Hospital of Yopougon
Statistics
Citations: 14
Authors: 14
Affiliations: 1
Identifiers
Doi:
10.1155/2013/583051
ISSN:
16879104
e-ISSN:
16879112
Research Areas
Cancer
Health System And Policy
Study Design
Cohort Study
Study Locations
Ivory Coast