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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Efficacy of intravenous immunoglobulin treatment in lupus erythematosus chorea
Clinical Rheumatology, Volume 26, No. 12, Year 2007
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Description
Chorea is a rare complication of systemic lupus erythematosus (SLE) and is strongly related to the presence of antiphospholipid antibodies. Various infections may also be triggering factors in the development of choreiform movements. Additionally, Salmonella infection is the most common opportunistic bacterial infection in SLE patients. We report a case of a 33-year-old woman with SLE who developed lupus erythematosus-associated chorea with multiple involuntary movements and cognitive disturbances. Because the methylprednisolone therapy administered appeared to lead to Salmonella enteritidis infection, intravenous immunoglobulin (IVIg) in a total dose 100 g was administered after which a remarkable improvement of the abnormal movements and cognitive function was noted. Within 7 days, the patient had returned to normal. We therefore conclude that IVIg therapy may be an effective therapeutic approach for the treatment of the acute cerebral complications of SLE, especially in cases in whom other therapeutic strategies are ineffective or harmful. © Clinical Rheumatology 2007.
Authors & Co-Authors
Lazurova, I.
Slovakia, Kosice
University Hospital L. Pasteur Kosice
MacEjova, Z.
Slovakia, Kosice
University Hospital L. Pasteur Kosice
Benhatchi, K.
Slovakia, Kosice
University Hospital L. Pasteur Kosice
Oetterová, M.
Slovakia, Kosice
University Hospital L. Pasteur Kosice
Antolová, E.
Slovakia, Kosice
Medical Faculty Hospital, Kosice
Asherson, Ronald A.
South Africa, Johannesburg
School of Pathology
Rovenskỳ, Jozef
Slovakia, Piest'any
Ná Ústav Reumatických Chorob
Statistics
Citations: 21
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1007/s10067-007-0627-9
ISSN:
07703198
Research Areas
Health System And Policy
Infectious Diseases
Participants Gender
Female