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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Anti‐HCV‐Positive Cirrhosis Associated with Schistosomiasis
The American Journal of Gastroenterology, Volume 88, No. 9, Year 1993
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Description
Hepatosplenic schistosomiasis is occasionally associated with cirrhosis and progressive hepatic decompensation. The aim of the present study was to determine the prevalence of antibody to hepatitis C virus in patients with schistosomiasis and cirrhosis. The prevalence of anti‐HCV was studied in 12 consecutive cases of schistosomiasis associated with biopsy proven cirrhosis. All patients had a past history of schistosomiasis and high liters of schistosomal antibodies in serum (1:32 to 1:4096). Five of the 12 patients had hepatic catheterization and were found to have sinusoidal involvement with corrected sinusoidal pressures ranging from 19 to 23 mm Hg. Four had ascites, six had pedal edema, and eight had peripheral signs of chronic liver disease in the form of palmar erythema, spider nevi, and/or gynecomastia. Ten of the 12 cases (83%) were repeatedly positive for anti‐HCV/ELISA. These results suggest that when patients with schistosomiasis develop cirrhosis, associated hepatitis C virus infection should be suspected. Copyright © 1993, Wiley Blackwell. All rights reserved
Authors & Co-Authors
Koshy, Abraham
Kuwait, Kuwait City
Kuwait University
Al-Nakib, Basil M.
Kuwait, Kuwait City
Kuwait University
Al‐Mufti, Siham
Kuwait, Kuwait City
Kuwait University
Madda, John Patrick
Kuwait, Kuwait City
Kuwait University
Ilira, P. R.
Kuwait, Kuwait City
Kuwait University
Statistics
Citations: 5
Authors: 5
Affiliations: 1
Identifiers
Doi:
10.1111/j.1572-0241.1993.tb07617.x
e-ISSN:
15720241
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study