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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Polyphenolic contents and antioxidant potential of stem bark extracts from jatropha curcas (Linn)
International Journal of Molecular Sciences, Volume 12, No. 5, Year 2011
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Description
We assessed the polyphenolic contents and antioxidant potential of the aqueous, ethanol and methanol stem bark extracts of Jatropha curcas. The total phenol, flavonoids, flavonols and proanthocyanidin contents of the extracts were evaluated to determine their effect on the antioxidant property of this plant, using standard phytochemical methods. The antioxidant and free radical scavenging activity of ethanol, methanol and aqueous extracts of the plant were also assessed against 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), ferric reducing, nitric oxide (NO), superoxide anion, (O 2-) and hydrogen peroxide (H 2O 2) using spectroscopic methods and results were compared with that of butylated hydroxyl toluene (BHT) and ascorbic acid as standards. The concentrations of different classes of phenolic compounds were higher in methanol and ethanol extracts compared to aqueous extracts. There was correlation between total phenol, total flavonoids, total flavonol and total proanthocyanidins (r = 0.996, 0.978, 0.908, and 0.985) respectively. There was correlations between the amount of phenolic compounds and percentage inhibition of DPPH radicals scavenging activity of the extract (r = 0.98). Findings from the present study indicated that J. curcas is a potential source of natural antioxidants and may be a good candidate for pharmaceutical plant based products. © 2011 by the authors.
Authors & Co-Authors
Igbinosa, Osamuyimen O.
United States, Philadelphia
Drexel University College of Medicine
Igbinosa, Isoken Henrietta
South Africa, Alice
University of Fort Hare
Chigor, Nnamdigadi Vincent
South Africa, Alice
University of Fort Hare
Uzunuigbe, Olohirere E.
Nigeria, Ekpoma
Ambrose Alli University
Oyedemi, Sunday Oyewole
South Africa, Alice
University of Fort Hare
Odjadjare, Emmanuel E.O.
South Africa, Alice
University of Fort Hare
Nigeria, Oghara
Western Delta University
Okoh, Anthony I.
South Africa, Alice
University of Fort Hare
Igbinosa, Etinosa O.
South Africa, Alice
University of Fort Hare
Nigeria, Ekpoma
Ambrose Alli University
Statistics
Citations: 89
Authors: 8
Affiliations: 4
Identifiers
Doi:
10.3390/ijms12052958
e-ISSN:
14220067