Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia
Diagnostic Microbiology and Infectious Disease, Volume 87, No. 3, Year 2017
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We have developed recombinant fragment C based rapid point of care dipstick devices to assess tetanus immunization status using plasma or whole blood. The devices demonstrated specificity of 0.90 and sensitivity of 0.90 (whole blood)/0.94 (plasma) at field sites in Bangladesh and The Gambia when compared to a commercial ELISA with the immune cut-off titer set as ≥0.1 IU/mL.