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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Partial characterization, antioxidative properties and hypolipidemic effects of oilseed cake of Allanblackia floribunda and Jatropha curcas
BMC Complementary and Alternative Medicine, Volume 13, Article 352, Year 2013
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Description
Background: High fat diet is known to induce oxidative stress and abnormal changes in lipid metabolism. Many traditional plants have been shown to possess antioxidant and lipid-lowering activities, improving on oxidative status and lipid profile. In this paper, we characterized and examined the antioxidative properties of the oilseed cake of A. floribunda and J. curcas. We also evaluated their effect on lipid profile in the plasma and liver of experimental rats placed on a high fat diet. Methods: For a partial characterization, the qualitative and quantitative analyses of storage proteins, dietary fibre and polyphenol content were evaluated. Four extracts (aqueous, ethanolic, methanolic and 0.1 N HCl) were evaluated for their antioxidant properties and scavenging activities. The effect on lipid profile was evaluated after the administration of the crude extracts to albino rats placed on a high fat diet. Results: Our results showed that J. curcas contains 10 times more storage proteins than A. floribunda while A. floribunda contains twice as much total dietary fibre than J. curcas. An evaluation of the different families of storage proteins showed that J. curcas has glutelins as the major storage proteins in its seeds (61.65 mg/g d.m), followed by globulins (25.30 mg/g d.m) and albumins (18.30 mg/g d.m). The electrophoretic analyses revealed a diversity of bands at the level of the different families and for both species. The evaluation of the in vitro antioxidant activities showed that A. floribunda extracts had higher antioxidant properties. Although the composition of A. floribunda and J. curcas oilseed cake are different, they lowered serum triglycerides (TG), total cholesterol (TC) and blood glucose level.Conclusion: These results show that the oilseed cake of A. floribunda and J. curcas possess antioxidant properties with an effect on blood glucose level and lipid profile. © 2013 Boudjeko et al.; licensee BioMed Central Ltd.
Authors & Co-Authors
Boudjeko, Thaddée
Cameroon, Yaounde
Biotechnology Centre
Cameroon, Yaounde
Université de Yaoundé I
Ngomoyogoli, Judith Emery Kanemoto
Cameroon, Yaounde
Biotechnology Centre
Woguia, Alice Louise
Cameroon, Yaounde
Université de Yaoundé I
Yanou, Nicolas Njintang
Cameroon, Ngaoundere
University of Ngaoundere
Statistics
Citations: 21
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1186/1472-6882-13-352
e-ISSN:
14726882
Study Approach
Qualitative
Quantitative