Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

medicine

Genetic analysis of primaquine tolerance in a patient with relapsing vivax malaria

Emerging Infectious Diseases, Volume 19, No. 5, Year 2013

Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide variants as candidate molecular markers of resistance.
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Citations: 9
Authors: 9
Affiliations: 7
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Research Areas
Genetics And Genomics
Health System And Policy
Infectious Diseases