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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Characteristics of persons who complied with and failed to comply with annual ivermectin treatment
Tropical Medicine and International Health, Volume 17, No. 7, Year 2012
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Description
Objective To assess individual compliance with annual ivermectin treatment in onchocerciasis-endemic villages. Methods Multi-site study in eight APOC-sponsored projects in Cameroon, Nigeria and Uganda to identify the socio-demographic correlates of compliance with ivermectin treatment. A structured questionnaire was administered on 2305 persons aged 10years and above. Two categories of respondents were purposively selected to obtain both high and low compliers: people who took ivermectin 6-8 times and 0-2 times previously. Simple descriptive statistics were employed in characterizing the respondents into high and low compliers, while some socio-demographic and key perceptual factors were employed in regression models constructed to explain levels of compliance among the respondents. Results Some demographic and perceptual factors associated with compliance were identified. Compliance was more common among men (54.4%) (P<0.001). Adults (54.6%) had greater rates of high compliance (P<0.001. The mean age of high compliers (41.5years) was significantly older (35.8years) (t=8.46, P<0.001). Perception of onchocerciasis and effectiveness of ivermectin influenced compliance. 81.4% of respondents saw benefits in annual ivermectin treatment, high compliance among those who saw benefits was 59.3% compared to 13.3% of those who did not (P<0.001). Conclusion Efforts to increase compliance with ivermectin treatment should focus on providing health education to youth and women. Health education should also highlight the benefits of taking ivermectin. © 2012 Blackwell Publishing Ltd.
Authors & Co-Authors
Brieger, William R.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Okeibunor, Joseph Chukwudi
Nigeria, Naukka
University of Nigeria
Abiose, Adenike O.
Nigeria, Ibadan
Sightcare International
Ndyomugyenyi, Richard
Uganda, Kampala
National Onchocerciasis Control Programme
Wanji, Samuel
Cameroon
Research Foundation in Tropical Diseases and Environment
Elhassan, Elizabeth Osim
United Kingdom, Chippenham
Sightsavers, United Kingdom
Amazigo, Uche V.
Burkina Faso, Ouagadougou
African Programme for Onchocerciasis Control
Statistics
Citations: 31
Authors: 7
Affiliations: 7
Identifiers
Doi:
10.1111/j.1365-3156.2012.03007.x
ISSN:
13602276
e-ISSN:
13653156
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Cameroon
Nigeria
Uganda
Participants Gender
Male
Female