Effect of copper on bioconcentration of benzotriazole ultraviolet stabilizers (BUVSs) in common carp (Cyprinus carpio)

Benzotriazole ultraviolet stabilizers (BUVSs) have received increasing attention as emerging contaminants. However, most of the existing relevant studies focused on the adverse ecological effect of BUVSs under their single exposure, information about the bioconcentration potential of BUVSs and their joint exposure with heavy metals remains scarce. In this study, we investigated the bioconcentration kinetics of 6 frequently reported BUVSs in four main tissues of common carp under different Cu concentration. The bioconcentration factors (BCFs) and half-lives (t1/2) in the fish tissues ranged from 5.73 (UV-PS in kidney) to 1076 (UV-327 in liver), and 2.19 (UV-PS in kidney) to 31.5 (UV-320 in liver) days, respectively. Under the effect of Cu, an increase in BCF values was observed, which is mainly due to the decreased depuration rate (k2). These results indicated that BUVSs accumulated in fish and that Cu can affect the bioconcentration of BUVSs. This study provides important insight into the co-exposure of heavy metal and BUVSs, contributing to the perfection of BUVSs risk assessment.