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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Outcomes and complications of catheter ablation for atrial fibrillation in females
Heart Rhythm, Volume 7, No. 2, Year 2010
Notification
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Description
Background: Most atrial fibrillation (AF) ablation studies have consisted predominantly of males; accordingly, there is a paucity of information on the safety and efficacy of catheter ablation in a large cohort of female AF patients. Objective: The purpose of this study was to evaluate catheter ablation for AF in female patients. Methods: From January 2005 to May 2008, 3265 females underwent pulmonary vein antrum isolation. Success rates, patient profiles, and complications were collected. Results: Approximately 16% of our population was female (P <.001). Females were older (59 ± 13 vs. 56 ± 19 years; P <.01) and had a lower prevalence of paroxysmal atrial fibrillation (PAF; 46% vs. 55%; P <.001). Females failed more antiarrhythmics (4 ± 1 vs. 2 ± 3; P = .04) and were referred later for catheter ablation (6.51 ± 7 vs. 4.85 ± 6.5 years; P = .02) than males. More females failed ablation (31.5% vs. 22.5%; P = .001) and had nonantral sites of firing than males (P <.001). Female patients had 11 (2.1%) hematomas versus 27 (0.9%) in males. Conclusions: Five times as many males underwent catheter ablation than females. Females failed more ablations possibly because of a higher prevalence of nonantral firing, non-PAF, and longer history of AF. Females had more bleeding complications than males. © 2010 Heart Rhythm Society.
Authors & Co-Authors
Patel, Dimpi
United States, Austin
Texas Cardiac Arrhythmia Institute
Mohanty, Prasant
United States, Austin
Texas Cardiac Arrhythmia Institute
Di Biase, Luigi
United States, Austin
Texas Cardiac Arrhythmia Institute
Italy, Foggia
Università Degli Studi Di Foggia
United States, Austin
The University of Texas at Austin
Sanchez, Javier E.
United States, Austin
Texas Cardiac Arrhythmia Institute
Shaheen, Mazen H.
United States, Cincinnati
University of Cincinnati
Burkhardt, J. David
United States, Austin
Texas Cardiac Arrhythmia Institute
Bassouni, Mohammed
Egypt, Giza
Cairo University
Cummings, Jennifer
United States, Akron
Akron General Hospital
Wang, Yan
United States, Austin
Texas Cardiac Arrhythmia Institute
Lewis, William R.
United States, Cleveland
Metrohealth Medical Center
Diaz, Alberto
United States, Cleveland
Metrohealth Medical Center
Horton, Rodney P.
United States, Austin
Texas Cardiac Arrhythmia Institute
United States, Austin
The University of Texas at Austin
Beheiry, Salwa
United States, San Francisco
California Pacific Medical Center
Hongo, Richard
United States, San Francisco
California Pacific Medical Center
Gallinghouse, G. Joseph
United States, Austin
Texas Cardiac Arrhythmia Institute
Zagrodzky, Jason D.
United States, Austin
Texas Cardiac Arrhythmia Institute
Bailey, Shane M.
United States, Austin
Texas Cardiac Arrhythmia Institute
Al-Ahmad, Amin
United States, Palo Alto
Stanford University
Wang, Paul
United States, Palo Alto
Stanford University
Schweikert, Robert A.
United States, Akron
Akron General Hospital
Natale, Andrea
United States, Austin
Texas Cardiac Arrhythmia Institute
United States, Austin
The University of Texas at Austin
Statistics
Citations: 221
Authors: 21
Affiliations: 9
Identifiers
Doi:
10.1016/j.hrthm.2009.10.025
ISSN:
15475271
Research Areas
Health System And Policy
Study Design
Cross Sectional Study
Cohort Study
Participants Gender
Female