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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Psychiatrists' awareness of adherence to antipsychotic medication in patients with schizophrenia: Results from a survey conducted across Europe, the Middle East, and Africa
Patient Preference and Adherence, Volume 7, Year 2013
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Description
Background: Nonadherence is common among patients with schizophrenia, although the rates vary according to means of assessment and patient population. Failure to adhere to medication can have a major impact on the course of illness and treatment outcomes, including increasing the risk of relapse and rehospitalization. Understanding psychiatrists' perception of the causes and consequences of nonadherence is crucial to addressing adherence problems effectively. Methods: The Europe, the Middle East, and Africa (EMEA) Spanish Adherencia Terapéutica en la Esquizofrenia (ADHES) survey was conducted by questionnaire during January-March 2010 among psychiatrists treating patients with schizophrenia in 36 countries. The survey comprised 20 questions. In addition to recording the demographic details of the 4722 respondents (~12% response rate), it canvassed their preferred methods of assessing adherence, their perceptions of adherence rates, reasons for nonadherence, and strategies to improve adherence. Results: Psychiatrists estimated that 53% of their patients with schizophrenia were partially/nonadherent during the previous month. They estimated only one-third of patients who deteriorated after stopping medication were able to attribute this to nonadherence. Psychiatrists assessed adherence most often by patient interview. Lack of insight was viewed as the most important cause of medication discontinuation, followed by patients feeling better and thinking their medication unnecessary, and experiencing undesirable side effects. Considerably fewer psychiatrists viewed insufficient efficacy, cognitive impairment, or drug/alcohol abuse as the most important reasons for their patients stopping medication. Conclusion: Psychiatrists throughout EMEA recognize the impact of partial/nonadherence to medication, with patient enquiry being the most commonly used means of assessment. There remains a need for more proactive management of patients with schizophrenia, particularly in increasing patient insight of their illness in order to improve adherence and minimize the consequences of relapse. Strategies focused on raising awareness of the importance of adherence are also warranted, with the aim of improving patient outcomes in schizophrenia. © 2013 Olivares et al, publisher and licensee Dove Medical Press Ltd.
Available Materials
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Authors & Co-Authors
Olivares, Jose
Spain, Vigo
Complejo Hospitalario Universitario de Vigo
Alpteki̇n, Köksal
Turkey, Izmir
Dokuz Eylül Üniversitesi
Azorin, Jean Michel
France, Marseille
Hôpital Sainte Marguerite
Cañas, Fernando
Spain, Madrid
Hospital Dr. Rodríguez Lafora
Dubois, Vincent
Belgium, Brussels
Cliniques Universitaires Saint-luc
Emsley, Robin Alexander
South Africa, Cape Town
Stellenbosch University, Faculty of Medicine and Health Sciences
Gorwood, Philip A.P.M.
France, Paris
Centre Hospitalier Sainte-anne
Haddad, Peter M.
United Kingdom, Manchester
The University of Manchester
Naber, Dieter
Germany, Hamburg
Universitätsklinikum Hamburg-eppendorf
Papageorgiou, George
Greece, Athens
Evagelismos Hospital
Roca, Miquel
Spain, Palma
Universitat de Les Illes Balears
Thomas, Pierre
France, Lille
Université de Lille
Martinez, Guadalupe
Spain, Madrid
Medical Affairs
Schreiner, Andreas
Germany, Neuss
Medical Affairs
Statistics
Citations: 14
Authors: 14
Affiliations: 14
Identifiers
Doi:
10.2147/PPA.S37534
e-ISSN:
1177889X
Research Areas
Health System And Policy
Mental Health
Substance Abuse
Study Design
Cross Sectional Study
Study Approach
Quantitative